Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 282305..283012 Replicon chromosome
Accession NZ_CP044097
Organism Citrobacter koseri strain FDAARGOS_646

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag FOB54_RS01345 Protein ID WP_148084109.1
Coordinates 282680..283012 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag FOB54_RS01340 Protein ID WP_123907366.1
Coordinates 282305..282646 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB54_RS01305 277458..278333 + 876 WP_123907372.1 GTPase family protein -
FOB54_RS01310 278577..279293 + 717 WP_123907371.1 WYL domain-containing protein -
FOB54_RS01315 279329..279781 + 453 WP_000734321.1 hypothetical protein -
FOB54_RS01320 279853..280326 + 474 WP_123907370.1 hypothetical protein -
FOB54_RS01325 280447..281268 + 822 WP_123907369.1 DUF945 domain-containing protein -
FOB54_RS01330 281299..281739 + 441 WP_123907368.1 antirestriction protein -
FOB54_RS01335 281752..282294 + 543 WP_123907367.1 DNA repair protein RadC -
FOB54_RS01340 282305..282646 + 342 WP_123907366.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
FOB54_RS01345 282680..283012 + 333 WP_148084109.1 TA system toxin CbtA family protein Toxin
FOB54_RS01350 283270..284277 + 1008 WP_047041139.1 restriction endonuclease -
FOB54_RS01355 285302..286672 + 1371 WP_049010418.1 tyrosine phenol-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 248564..284277 35713


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(4-106)

Antitoxin

Antitoxin CbeA

(13-111)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12400.24 Da        Isoelectric Point: 5.6618

>T140042 WP_148084109.1 NZ_CP044097:282680-283012 [Citrobacter koseri]
MLSTTPQAATLCLSPVAVWQMLLACLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYELVRIDRRGFNWQ
EQSPYLRAVDILRARQATGLLKRNRISAAQ

Download         Length: 333 bp

>T140042 NZ_CP058879:3204478-3204864 [Escherichia coli]
ATGGGTGTGTATAAGGCAAGACGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAGGGCATATGGGAAGCTGATTTAGGTAGCGGTGTCATCAAAAAACGTTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAGGAGTGGT
CTAAGCAGTAAAGGAACCAAAGAAATCGAAGATGATGAACTGGCGGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTTTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12754.29 Da        Isoelectric Point: 6.7482

>AT140042 WP_123907366.1 NZ_CP044097:282305-282646 [Citrobacter koseri]
MKSTGSESDSFLKWGLNRNVTPFFGARLVQEGNRLHYLADRASISGEFSNAESLKLNEVFPHFISQMESMLTTGEMNPRH
AHCVTLYHNGFTCEADTLGSYGYVYIAVYPTHR

Download         Length: 342 bp

>AT140042 NZ_CP058879:3204854-3205183 [Escherichia coli]
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAAGTTGA
TGCCATTGCCGTCATGGTCAAAGCTCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGTAATGAAATAAAACCGAGCGGCCCGGCATTACGTATTTTGAATACATTGGCAATAAAAGGGCCGGAAGTTTT
TGCAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References