Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1311993..1312641 Replicon chromosome
Accession NZ_CP044092
Organism Stenotrophomonas maltophilia strain FDAARGOS_649

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FOB57_RS05840 Protein ID WP_005407702.1
Coordinates 1312336..1312641 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FOB57_RS05835 Protein ID WP_005407703.1
Coordinates 1311993..1312295 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB57_RS05800 1307433..1307654 - 222 WP_004153772.1 CsbD family protein -
FOB57_RS05805 1307862..1307999 - 138 WP_005407710.1 entericidin A/B family lipoprotein -
FOB57_RS05810 1308160..1309080 - 921 WP_005407709.1 arginase -
FOB57_RS05815 1309211..1309558 + 348 WP_005411961.1 hypothetical protein -
FOB57_RS05820 1309583..1310353 - 771 WP_005411960.1 DUF3011 domain-containing protein -
FOB57_RS05825 1310948..1311355 + 408 WP_005407705.1 hypothetical protein -
FOB57_RS05830 1311436..1311758 + 323 Protein_1138 hypothetical protein -
FOB57_RS05835 1311993..1312295 - 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
FOB57_RS05840 1312336..1312641 - 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOB57_RS05850 1312949..1313803 - 855 WP_005411958.1 SPOR domain-containing protein -
FOB57_RS05855 1313813..1314544 - 732 WP_005407698.1 type III pantothenate kinase -
FOB57_RS05860 1314541..1315506 - 966 WP_043035430.1 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor -
FOB57_RS05865 1315651..1315929 + 279 WP_005407696.1 hypothetical protein -
FOB57_RS05870 1315896..1316687 + 792 WP_165931275.1 zinc-dependent peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T140039 WP_005407702.1 NZ_CP044092:c1312641-1312336 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

>T140039 NZ_CP058879:c2134928-2134821 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT140039 WP_005407703.1 NZ_CP044092:c1312295-1311993 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp

>AT140039 NZ_CP058879:2134975-2135041 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References