140009

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 890558..891090 Replicon chromosome
Accession NZ_CP044081
Organism Paracoccus yeei strain FDAARGOS_643

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag FOB51_RS08105 Protein ID WP_120441940.1
Coordinates 890842..891090 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag FOB51_RS08100 Protein ID WP_150350253.1
Coordinates 890558..890845 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB51_RS08070 886304..886510 + 207 WP_150350247.1 hypothetical protein -
FOB51_RS08075 886512..886928 + 417 WP_150350248.1 hypothetical protein -
FOB51_RS08080 886925..887215 + 291 WP_150350249.1 hypothetical protein -
FOB51_RS08085 887212..887688 + 477 WP_150350250.1 hypothetical protein -
FOB51_RS08090 887689..890184 + 2496 WP_150350251.1 tape measure protein -
FOB51_RS08095 890184..890450 + 267 WP_150350252.1 hypothetical protein -
FOB51_RS08100 890558..890845 - 288 WP_150350253.1 BrnA antitoxin family protein Antitoxin
FOB51_RS08105 890842..891090 - 249 WP_120441940.1 BrnT family toxin Toxin
FOB51_RS08115 891483..892568 + 1086 WP_150350254.1 NUDIX domain-containing protein -
FOB51_RS08120 892645..893676 + 1032 WP_080621861.1 cysteine synthase A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 881113..891090 9977


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-78)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(20-93)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 8988.43 Da        Isoelectric Point: 6.4582

>T140009 WP_120441940.1 NZ_CP044081:c891090-890842 [Paracoccus yeei]
MTMIVWDEPKRLTNLAKHGLDFADLDEQFFLDSVVVPAKGGRHMAIGRMSDGTIAVVFATLGTEGVSVISMRPASQKERN
LL

Download         Length: 249 bp

>T140009 NZ_CP058874:2475713-2477029 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAATGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGATCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAACAGCTCACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTGCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTGTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTATTGGGTGGTGCAGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTTCCGCAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACCGTCGGTTAAGCCGAGAATGGTATTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10561.98 Da        Isoelectric Point: 10.4689

>AT140009 WP_150350253.1 NZ_CP044081:c890845-890558 [Paracoccus yeei]
MTRKHLTEEQIQRMIASDPDAPEATDDQIAQARPFTDAFPALADAMRKNTGGRPKSANPKVAVSLRLDRDVVERFKTSGP
GWQSRMNAILRDAKV

Download         Length: 288 bp

>AT140009 NZ_CP058874:2475447-2475713 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TGACGACCTTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References