Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 1804053..1804600 | Replicon | chromosome |
| Accession | NZ_CP044069 | ||
| Organism | Vibrio vulnificus strain FDAARGOS_663 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A3RE16 |
| Locus tag | FOB71_RS15585 | Protein ID | WP_017420363.1 |
| Coordinates | 1804053..1804355 (-) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A3RE15 |
| Locus tag | FOB71_RS15590 | Protein ID | WP_017420364.1 |
| Coordinates | 1804343..1804600 (-) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FOB71_RS15540 | 1799768..1801300 | - | 1533 | Protein_1559 | IS3 family transposase | - |
| FOB71_RS15545 | 1801327..1802088 | - | 762 | WP_089529815.1 | TIM44-like domain-containing protein | - |
| FOB71_RS15550 | 1802115..1802237 | - | 123 | WP_081111495.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15555 | 1802603..1802713 | - | 111 | WP_072599523.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15560 | 1802770..1803018 | + | 249 | WP_005377003.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| FOB71_RS15565 | 1803008..1803298 | + | 291 | WP_005377002.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FOB71_RS15570 | 1803438..1803851 | - | 414 | WP_017420361.1 | VOC family protein | - |
| FOB71_RS15580 | 1803925..1804017 | - | 93 | WP_017420362.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15585 | 1804053..1804355 | - | 303 | WP_017420363.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| FOB71_RS15590 | 1804343..1804600 | - | 258 | WP_017420364.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| FOB71_RS15595 | 1804671..1804742 | - | 72 | WP_072599534.1 | hypothetical protein | - |
| FOB71_RS15600 | 1804844..1805263 | + | 420 | WP_017420365.1 | BLUF domain-containing protein | - |
| FOB71_RS15610 | 1805399..1805578 | - | 180 | WP_080586392.1 | hypothetical protein | - |
| FOB71_RS15615 | 1805775..1805897 | - | 123 | WP_080586394.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15625 | 1806263..1806373 | - | 111 | WP_017420369.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15630 | 1806370..1806786 | - | 417 | WP_026060790.1 | VOC family protein | - |
| FOB71_RS15635 | 1806813..1806941 | - | 129 | WP_080586393.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15640 | 1806895..1807818 | - | 924 | WP_017420366.1 | FRG domain-containing protein | - |
| FOB71_RS15645 | 1807797..1807904 | - | 108 | WP_100222774.1 | iron transporter | - |
| FOB71_RS15650 | 1807961..1808495 | - | 535 | Protein_1578 | GNAT family N-acetyltransferase | - |
| FOB71_RS15655 | 1808455..1808646 | - | 192 | WP_080586391.1 | DUF3265 domain-containing protein | - |
| FOB71_RS15660 | 1808980..1809108 | - | 129 | WP_115173855.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1799768..1962721 | 162953 | |
| - | inside | Integron | - | - | 1801327..1962721 | 161394 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11611.53 Da Isoelectric Point: 5.8692
>T139988 WP_017420363.1 NZ_CP044069:c1804355-1804053 [Vibrio vulnificus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGGKV
FILFVMRAERDLRKFLLSKQ
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGGKV
FILFVMRAERDLRKFLLSKQ
Download Length: 303 bp
>T139988 NZ_CP058869:1939612-1939714 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 86 a.a. Molecular weight: 9620.12 Da Isoelectric Point: 6.7269
>AT139988 WP_017420364.1 NZ_CP044069:c1804600-1804343 [Vibrio vulnificus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVLSHDEAKDKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVLSHDEAKDKM
SKWLK
Download Length: 258 bp
>AT139988 NZ_CP058869:c1939721-1939576 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|