Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 558539..558684 Replicon chromosome
Accession NZ_CP044039
Organism Klebsiella pneumoniae strain FDAARGOS_630

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 558575..558677 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 558539..558684 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB38_RS05000 553669..555729 + 2061 WP_004151449.1 oligopeptidase B -
FOB38_RS05005 555733..556392 - 660 WP_002911407.1 exodeoxyribonuclease X -
FOB38_RS05010 556471..556701 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FOB38_RS05015 556814..557188 + 375 WP_039819395.1 CopC domain-containing protein YobA -
FOB38_RS05020 557192..558061 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
FOB38_RS05025 558078..558416 + 339 WP_002911404.1 YebY family protein -
- 558539..558684 - 146 - - Antitoxin
- 558575..558677 + 103 - - Toxin
FOB38_RS05035 559053..559196 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
FOB38_RS05040 559301..560269 - 969 WP_014907334.1 VirK/YbjX family protein -
FOB38_RS05045 560426..561079 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
FOB38_RS05050 561076..561267 - 192 WP_002911395.1 YebW family protein -
FOB38_RS05055 561365..561604 - 240 WP_002911393.1 YebV family protein -
FOB38_RS05060 561720..563153 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T139912 NZ_CP044039:558575-558677 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT139912 NZ_CP044039:c558684-558539 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References