Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3248965..3249105 Replicon chromosome
Accession NZ_CP044033
Organism Klebsiella pneumoniae strain FDAARGOS_631

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3249001..3249103 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3248965..3249105 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB39_RS16155 3244095..3246155 + 2061 WP_004148850.1 oligopeptidase B -
FOB39_RS16160 3246159..3246818 - 660 WP_002911407.1 exodeoxyribonuclease X -
FOB39_RS16165 3246897..3247127 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FOB39_RS16170 3247240..3247614 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FOB39_RS16175 3247618..3248487 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
FOB39_RS16180 3248504..3248842 + 339 WP_002911404.1 YebY family protein -
- 3248965..3249105 - 141 - - Antitoxin
- 3249001..3249103 + 103 - - Toxin
FOB39_RS16185 3249181..3250266 - 1086 WP_150330954.1 phage integrase Arm DNA-binding domain-containing protein -
FOB39_RS16190 3250235..3250507 - 273 WP_150330955.1 excisionase -
FOB39_RS16195 3250623..3250880 - 258 WP_064153511.1 DNA polymerase III subunit theta -
FOB39_RS16200 3251300..3251494 - 195 WP_032425654.1 TraR/DksA family transcriptional regulator -
FOB39_RS16205 3251491..3251763 - 273 WP_049001955.1 DUF5405 family protein -
FOB39_RS16215 3252070..3252552 - 483 WP_049001950.1 siphovirus Gp157 family protein -
FOB39_RS16220 3252545..3253456 - 912 WP_150330956.1 recombinase RecT -
FOB39_RS16225 3253453..3253761 - 309 WP_150330957.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3244128..3302550 58422


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T139896 NZ_CP044033:3249001-3249103 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT139896 NZ_CP044033:c3249105-3248965 [Klebsiella pneumoniae]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References