139873

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 299458..300054 Replicon chromosome
Accession NZ_CP044009
Organism Rhizobium sp. BG6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F3Y33_RS01515 Protein ID WP_153269749.1
Coordinates 299809..300054 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F3Y33_RS01510 Protein ID WP_153269750.1
Coordinates 299458..299805 (-) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3Y33_RS01490 296277..296507 - 231 WP_153269754.1 type II toxin-antitoxin system ParD family antitoxin -
F3Y33_RS01495 296694..297242 - 549 WP_153269753.1 HdeD family acid-resistance protein -
F3Y33_RS01500 297382..297981 + 600 WP_153269752.1 transcriptional regulator BetI -
F3Y33_RS01505 297978..299447 + 1470 WP_153269751.1 betaine-aldehyde dehydrogenase -
F3Y33_RS01510 299458..299805 - 348 WP_153269750.1 helix-turn-helix transcriptional regulator Antitoxin
F3Y33_RS01515 299809..300054 - 246 WP_153269749.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
F3Y33_RS01520 300111..301760 + 1650 WP_203437352.1 choline dehydrogenase -
F3Y33_RS01525 301925..303286 + 1362 WP_153269748.1 chloride channel protein -
F3Y33_RS01530 303283..303654 - 372 WP_153269747.1 type II toxin-antitoxin system VapC family toxin -
F3Y33_RS01535 303648..303866 - 219 WP_153269746.1 ribbon-helix-helix domain-containing protein -
F3Y33_RS01540 303962..304408 - 447 WP_153269745.1 Rrf2 family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(58-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8927.44 Da        Isoelectric Point: 11.1284

>T139873 WP_153269749.1 NZ_CP044009:c300054-299809 [Rhizobium sp. BG6]
MRAVSYTKAASKSLSRMQPKRQAAIRAKVDAFARGEAVDLKRLTGSSLVRIRVDDDRVIIDEQTGLVLVIKVGPRGGIYK
E

Download         Length: 246 bp

>T139873 NZ_CP058839:3722531-3722818 [Shigella flexneri]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12826.69 Da        Isoelectric Point: 4.2793

>AT139873 WP_153269750.1 NZ_CP044009:c299805-299458 [Rhizobium sp. BG6]
MGSFEKTVIGGKPFVLVPEEEFEDMLDIIDANRIMARVAAGEETFPAELVYELLETDSRIRTYRIYRKMTATELAEAVGI
SQPYLSDIENGKKSGSVDVLKRIAVALRVDLDDIA

Download         Length: 348 bp

>AT139873 NZ_CP058839:3722805-3723107 [Shigella flexneri]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGGCGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References