Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 4769366..4769952 | Replicon | chromosome |
Accession | NZ_CP044006 | ||
Organism | Pseudomonas aeruginosa strain E90 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | G8CP73 |
Locus tag | FVA82_RS22750 | Protein ID | WP_003120987.1 |
Coordinates | 4769653..4769952 (-) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | FVA82_RS22745 | Protein ID | WP_003448662.1 |
Coordinates | 4769366..4769656 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FVA82_RS22725 | 4764517..4764726 | + | 210 | WP_003105733.1 | cold-shock protein | - |
FVA82_RS22730 | 4764948..4766837 | + | 1890 | WP_016851610.1 | hypothetical protein | - |
FVA82_RS22735 | 4766834..4768810 | + | 1977 | WP_016851611.1 | DEAD/DEAH box helicase | - |
FVA82_RS22740 | 4768951..4769295 | + | 345 | WP_016851612.1 | hypothetical protein | - |
FVA82_RS22745 | 4769366..4769656 | - | 291 | WP_003448662.1 | putative addiction module antidote protein | Antitoxin |
FVA82_RS22750 | 4769653..4769952 | - | 300 | WP_003120987.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FVA82_RS22755 | 4770154..4771278 | + | 1125 | WP_012076859.1 | TcpQ domain-containing protein | - |
FVA82_RS22760 | 4771278..4772987 | + | 1710 | WP_012076860.1 | PilN family type IVB pilus formation outer membrane protein | - |
FVA82_RS22765 | 4772991..4774316 | + | 1326 | WP_003099758.1 | type 4b pilus protein PilO2 | - |
FVA82_RS22770 | 4774306..4774839 | + | 534 | WP_003099760.1 | type IV pilus biogenesis protein PilP | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 4742387..4839256 | 96869 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11133.88 Da Isoelectric Point: 10.4495
>T139871 WP_003120987.1 NZ_CP044006:c4769952-4769653 [Pseudomonas aeruginosa]
MVEVKQTATFMAWESKLKDRRAKAVIAARIFRLANGLPGDVSPVGQGVSELRIHYGPGYRVYFQQRGTEIVILLCGGDKS
SQARDIEMAKRLANEWRPQ
MVEVKQTATFMAWESKLKDRRAKAVIAARIFRLANGLPGDVSPVGQGVSELRIHYGPGYRVYFQQRGTEIVILLCGGDKS
SQARDIEMAKRLANEWRPQ
Download Length: 300 bp
>T139871 NZ_CP058839:c2820532-2820425 [Shigella flexneri]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10394.91 Da Isoelectric Point: 4.7527
>AT139871 WP_003448662.1 NZ_CP044006:c4769656-4769366 [Pseudomonas aeruginosa]
MTEQIYDYDPAQALDSPEAMALFIADALDTGDTAYIAKAMGVVARAKGMTELAKETGLAREQLYKSFSERGNPTLKTMLA
VMRALGVDLTARPHAQ
MTEQIYDYDPAQALDSPEAMALFIADALDTGDTAYIAKAMGVVARAKGMTELAKETGLAREQLYKSFSERGNPTLKTMLA
VMRALGVDLTARPHAQ
Download Length: 291 bp
>AT139871 NZ_CP058839:2820580-2820646 [Shigella flexneri]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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