Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013644..2013915 Replicon chromosome
Accession NZ_CP043937
Organism Escherichia coli strain RM14516

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013682..2013785 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013644..2013915 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FS841_RS09670 2010801..2012240 + 1440 Protein_1895 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FS841_RS09675 2012358..2012594 + 237 WP_001295499.1 YebV family protein -
FS841_RS09680 2012699..2012890 + 192 WP_001296140.1 YebW family protein -
FS841_RS09685 2012891..2013547 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2013644..2013915 + 272 - - Antitoxin
- 2013682..2013785 - 104 - - Toxin
FS841_RS09690 2013943..2014284 - 342 WP_000976481.1 YebY family protein -
FS841_RS09695 2014297..2015169 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
FS841_RS09700 2015173..2015547 - 375 WP_000168743.1 CopC domain-containing protein YobA -
FS841_RS09705 2015686..2015916 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FS841_RS09710 2016018..2016674 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
FS841_RS09715 2016698..2017360 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2005414..2037701 32287


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T139520 NZ_CP043937:c2013785-2013682 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT139520 NZ_CP043937:2013644-2013915 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References