Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2895123..2895791 Replicon chromosome
Accession NZ_CP043929
Organism Methylomonas rhizoryzae strain GJ1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F1E05_RS12915 Protein ID WP_150049089.1
Coordinates 2895375..2895791 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F1E05_RS12910 Protein ID WP_150049087.1
Coordinates 2895123..2895374 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1E05_RS12895 2890640..2892739 - 2100 WP_150049081.1 excinuclease ABC subunit UvrB -
F1E05_RS12900 2893008..2894171 + 1164 WP_150049083.1 Fic family protein -
F1E05_RS12905 2894444..2894767 + 324 WP_150049085.1 type II toxin-antitoxin system VapC family toxin -
F1E05_RS12910 2895123..2895374 + 252 WP_150049087.1 plasmid stabilization protein Antitoxin
F1E05_RS12915 2895375..2895791 + 417 WP_150049089.1 type II toxin-antitoxin system VapC family toxin Toxin
F1E05_RS12920 2896014..2896640 + 627 WP_150049091.1 hypothetical protein -
F1E05_RS12925 2896624..2897619 + 996 WP_150049093.1 DUF262 domain-containing protein -
F1E05_RS12930 2897801..2898331 - 531 WP_150049095.1 transposase -
F1E05_RS12935 2898379..2898639 - 261 WP_150049097.1 hypothetical protein -
F1E05_RS12940 2898769..2899047 + 279 WP_150049099.1 BrnT family toxin -
F1E05_RS12945 2899001..2899303 + 303 WP_150049101.1 BrnA antitoxin family protein -
F1E05_RS12950 2899442..2899696 + 255 WP_150049103.1 type II toxin-antitoxin system HicA family toxin -
F1E05_RS12955 2899693..2900025 + 333 WP_150049105.1 type II toxin-antitoxin system HicB family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14825.12 Da        Isoelectric Point: 4.6286

>T139475 WP_150049089.1 NZ_CP043929:2895375-2895791 [Methylomonas rhizoryzae]
MIVLDTNVISEAMRPEPHPAVLAWLNEQVAETLYLPAITLAELLFGIAALPTGKRKDMLTKILEGLLQLFGDRVLPFDTD
AARQYAELAITARTGGQGFPTPDGYIAAIAASRGFVVASRDTAPYKAAGVSVINPWET

Download         Length: 417 bp

>T139475 NZ_CP058709:c1879744-1879346 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACAGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9338.68 Da        Isoelectric Point: 4.5578

>AT139475 WP_150049087.1 NZ_CP043929:2895123-2895374 [Methylomonas rhizoryzae]
MAMLTVRNLPDDVHRALRVRAAQHGRSTEAEVREILTMSVKPEERIRMGEALMALGRQIGLTDEDVEVFEQIEDKAPADP
VEV

Download         Length: 252 bp

>AT139475 NZ_CP058709:c1880040-1879747 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATTACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGAGCT
GAAAAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References