Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2596176..2596684 Replicon chromosome
Accession NZ_CP043929
Organism Methylomonas rhizoryzae strain GJ1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F1E05_RS11570 Protein ID WP_150048602.1
Coordinates 2596424..2596684 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag F1E05_RS11565 Protein ID WP_150048600.1
Coordinates 2596176..2596427 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1E05_RS11530 2591604..2592029 - 426 WP_150048588.1 ATP-binding protein -
F1E05_RS11535 2592045..2592377 - 333 WP_150048590.1 STAS domain-containing protein -
F1E05_RS11540 2592675..2594378 - 1704 WP_150048592.1 urease subunit alpha -
F1E05_RS11545 2594375..2594692 - 318 WP_150048594.1 urease subunit beta -
F1E05_RS11550 2595041..2595343 - 303 WP_150048596.1 urease subunit gamma -
F1E05_RS11555 2595407..2595799 - 393 WP_190303321.1 type II toxin-antitoxin system VapC family toxin -
F1E05_RS11560 2595799..2596059 - 261 WP_150048598.1 hypothetical protein -
F1E05_RS11565 2596176..2596427 + 252 WP_150048600.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F1E05_RS11570 2596424..2596684 + 261 WP_150048602.1 Txe/YoeB family addiction module toxin Toxin
F1E05_RS11580 2597130..2597660 - 531 WP_150048604.1 transposase -
F1E05_RS11585 2597726..2597941 - 216 WP_197737357.1 hypothetical protein -
F1E05_RS11590 2600604..2600900 - 297 WP_150048606.1 CRISPR-associated endonuclease Cas2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10292.83 Da        Isoelectric Point: 10.0668

>T139474 WP_150048602.1 NZ_CP043929:2596424-2596684 [Methylomonas rhizoryzae]
VKIRFSSDAWDSYLYWQATDKAILKRINQLIKEIQRQPFEGIGKPEPLKHGLSGYWSRRINDEHRIVYKIAGNTLLIAQL
RFHYEY

Download         Length: 261 bp

>T139474 NZ_CP058709:1641088-1641306 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9119.38 Da        Isoelectric Point: 4.4607

>AT139474 WP_150048600.1 NZ_CP043929:2596176-2596427 [Methylomonas rhizoryzae]
MDAISYSAARANLAKTMDKVCADHAPIIITRKSESPVVMLSLEDFQAMEETAYLLRSPANARRLLESIAELESGQGAEHE
LIE

Download         Length: 252 bp

>AT139474 NZ_CP058709:1640688-1641062 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References