Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1364335..1364818 Replicon chromosome
Accession NZ_CP043929
Organism Methylomonas rhizoryzae strain GJ1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag F1E05_RS06385 Protein ID WP_150047500.1
Coordinates 1364555..1364818 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag F1E05_RS06380 Protein ID WP_150047499.1
Coordinates 1364335..1364565 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1E05_RS06365 1359338..1359877 + 540 WP_150047496.1 C40 family peptidase -
F1E05_RS06370 1360033..1363359 + 3327 WP_150047497.1 EAL domain-containing protein -
F1E05_RS06375 1363505..1364302 - 798 WP_150047498.1 indole-3-glycerol phosphate synthase TrpC -
F1E05_RS06380 1364335..1364565 - 231 WP_150047499.1 CopG family transcriptional regulator Antitoxin
F1E05_RS06385 1364555..1364818 - 264 WP_150047500.1 BrnT family toxin Toxin
F1E05_RS06390 1364882..1365889 - 1008 WP_150047501.1 anthranilate phosphoribosyltransferase -
F1E05_RS06395 1365921..1366379 - 459 WP_150047502.1 DUF411 domain-containing protein -
F1E05_RS06400 1366446..1366865 - 420 WP_150047503.1 secondary thiamine-phosphate synthase enzyme YjbQ -
F1E05_RS06405 1367141..1368154 - 1014 WP_150047504.1 IS630 family transposase -
F1E05_RS06410 1368220..1368747 - 528 WP_150051830.1 GNAT family N-acetyltransferase -
F1E05_RS06415 1368773..1369495 - 723 WP_150047505.1 phosphate signaling complex protein PhoU -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10278.87 Da        Isoelectric Point: 9.8798

>T139471 WP_150047500.1 NZ_CP043929:c1364818-1364555 [Methylomonas rhizoryzae]
MITFEFDETKNRTNLLKHGIDFVDAQALWKDPRLLEIPAKTEDEPRYLVMGKIKGKHWSAVITYRSKNIRLISVRRSRTE
EIALYES

Download         Length: 264 bp

>T139471 NZ_CP058709:c666158-665982 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8820.10 Da        Isoelectric Point: 4.8151

>AT139471 WP_150047499.1 NZ_CP043929:c1364565-1364335 [Methylomonas rhizoryzae]
MKAKDFEQQFDDDVDITAAIDVSKAKRILQEQKRVNVDFPTWMIESLDREAGKLGVTRQSIIKVWLAERLEKIAQD

Download         Length: 231 bp

>AT139471 NZ_CP058709:c665936-665520 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References