Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 428574..429213 Replicon chromosome
Accession NZ_CP043909
Organism Acinetobacter sp. C16S1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag F2A31_RS02095 Protein ID WP_150024964.1
Coordinates 428818..429213 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag F2A31_RS02090 Protein ID WP_150024963.1
Coordinates 428574..428831 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F2A31_RS02065 423647..424012 + 366 WP_004641032.1 50S ribosomal protein L17 -
F2A31_RS02070 424176..424673 + 498 WP_150024959.1 GNAT family N-acetyltransferase -
F2A31_RS02075 425051..426541 + 1491 WP_150024960.1 NAD(P)/FAD-dependent oxidoreductase -
F2A31_RS02080 426665..427162 + 498 WP_150024961.1 DUF2059 domain-containing protein -
F2A31_RS02085 427214..428386 - 1173 WP_150024962.1 acyl-CoA dehydrogenase family protein -
F2A31_RS02090 428574..428831 + 258 WP_150024963.1 succinate dehydrogenase assembly factor 2 Antitoxin
F2A31_RS02095 428818..429213 + 396 WP_150024964.1 hypothetical protein Toxin
F2A31_RS02100 429424..429630 + 207 WP_171490620.1 hypothetical protein -
F2A31_RS02105 429990..431033 + 1044 WP_150024966.1 hypothetical protein -
F2A31_RS02110 431160..431741 + 582 WP_150024967.1 rhombosortase -
F2A31_RS02115 431919..434129 + 2211 WP_150024968.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 16016.15 Da        Isoelectric Point: 9.2511

>T139458 WP_150024964.1 NZ_CP043909:428818-429213 [Acinetobacter sp. C16S1]
MSTVSRVFVLKRSRFAFAFQLFVFISLTGLLYSLLPWFLWLISLLSMLIAWFQLLKQPQLKHFEYLDDQFCSFSFSDELE
EVQQRKIRKMIDHQCYIVICFYESQCRPCVIWWDQLSILQWKKLKKWVKLV

Download         Length: 396 bp

>T139458 NZ_CP058685:16663-16929 [Escherichia coli]
ATGAAGGTACGAAAAGGTGACAGGCAATATTATTTGAATAAAGAAGGTAATATGTTTCATCTTGTGAAACGGGTGAAGAC
CTTTTCTAAATCTGCGACTTTAGGAAAAACGAAAGCAACGGTGAAAACTGTTGCTGATCTTGTTTTTAATGAGAAGGCAT
TCGACACAATAGACTTTTCCAGAGATGGATTAAGAGAGAATGATAAAGAAATTGTTTCTATGATGATTCAGGAAATGAAC
AATGAACGAGGAAAAAATGTTAACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9982.46 Da        Isoelectric Point: 4.4558

>AT139458 WP_150024963.1 NZ_CP043909:428574-428831 [Acinetobacter sp. C16S1]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNCYLTADAAEKALFAELVEQEDPDLLDWFMEVGDPPRAELKAFILKLK
QYVHG

Download         Length: 258 bp

>AT139458 NZ_CP058685:16919-17161 [Escherichia coli]
ATGTTAACTGAAAACACACCAGAAAACATCAAACGTCTGCGGCAAAAAATTGGCCTGACGCAAAGAGAATGTGCTGAAAT
ATTCAGCATGAACCCGCGAACCTGGCGTCGCAAGGAAGAACCTGCCGGAACTGCAAGCGGTACAGCACTTACACCAGTAG
AGTTTAAATATCTTCAGCTTTTAGCTGGGGAACATCCTGAATACGTCCTGCGCAAAAGGGATAAACCTAAATGTAGTGAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References