139451

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 3800343..3801106 Replicon chromosome
Accession NZ_CP043902
Organism Shewanella sp. LC6

Toxin (Protein)


Gene name ataT Uniprot ID A0A501Y1C9
Locus tag FJD32_RS17075 Protein ID WP_029627974.1
Coordinates 3800600..3801106 (+) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A501XZ00
Locus tag FJD32_RS17070 Protein ID WP_032481064.1
Coordinates 3800343..3800609 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJD32_RS17055 3797231..3797923 - 693 WP_029627977.1 DsbC family protein -
FJD32_RS17060 3798265..3799203 + 939 WP_029627976.1 Abi family protein -
FJD32_RS17065 3799629..3800165 + 537 WP_029627975.1 hypothetical protein -
FJD32_RS17070 3800343..3800609 + 267 WP_032481064.1 DUF1778 domain-containing protein Antitoxin
FJD32_RS17075 3800600..3801106 + 507 WP_029627974.1 GNAT family N-acetyltransferase Toxin
FJD32_RS17080 3801147..3801533 - 387 WP_029627973.1 hypothetical protein -
FJD32_RS17085 3801530..3802102 - 573 WP_001944091.1 type IV conjugative transfer system lipoprotein TraV -
FJD32_RS17090 3802177..3803466 - 1290 WP_109247980.1 TraB/VirB10 family protein -
FJD32_RS17095 3803466..3804365 - 900 WP_109247985.1 type-F conjugative transfer system secretin TraK -
FJD32_RS17100 3804349..3804975 - 627 WP_000667170.1 hypothetical protein -
FJD32_RS17105 3804972..3805253 - 282 WP_000433891.1 type IV conjugative transfer system protein TraL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18320.04 Da        Isoelectric Point: 6.7043

>T139451 WP_029627974.1 NZ_CP043902:3800600-3801106 [Shewanella sp. LC6]
MGISAPTLLADEHQINAFQCGIEELDTWLRKQALKSQKRGTARVYVVNDTDAHQVVGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDDTAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Download         Length: 507 bp

>T139451 NZ_CP058682:4918107-4918448 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCACCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCAGGATTTTATTGGGGTAATTAC
CGGTAAACAGAAAGTCGCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9941.46 Da        Isoelectric Point: 7.0146

>AT139451 WP_032481064.1 NZ_CP043902:3800343-3800609 [Shewanella sp. LC6]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRANPQTLEGMKDL
FKRKAPWE

Download         Length: 267 bp

>AT139451 NZ_CP058682:c4918112-4918036 [Escherichia coli]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A501Y1C9

Antitoxin

Source ID Structure
AlphaFold DB A0A501XZ00

References