Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 1674849..1675665 | Replicon | chromosome |
Accession | NZ_CP043902 | ||
Organism | Shewanella sp. LC6 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | A0A252EQR5 |
Locus tag | FJD32_RS07625 | Protein ID | WP_069455295.1 |
Coordinates | 1674849..1675250 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | A0A501X4H4 |
Locus tag | FJD32_RS07630 | Protein ID | WP_069455294.1 |
Coordinates | 1675243..1675665 (-) | Length | 141 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FJD32_RS07595 | 1669951..1671159 | - | 1209 | WP_001206290.1 | IS4-like element IS10A family transposase | - |
FJD32_RS07600 | 1671198..1671644 | - | 447 | WP_205403038.1 | hypothetical protein | - |
FJD32_RS07605 | 1671748..1672347 | - | 600 | WP_069455299.1 | metallophosphoesterase | - |
FJD32_RS07610 | 1672356..1672769 | - | 414 | WP_069455298.1 | hypothetical protein | - |
FJD32_RS07615 | 1672766..1673068 | - | 303 | WP_205403039.1 | hypothetical protein | - |
FJD32_RS07620 | 1673624..1674655 | + | 1032 | WP_069455296.1 | dTDP-glucose 4,6-dehydratase | - |
FJD32_RS07625 | 1674849..1675250 | - | 402 | WP_069455295.1 | type II toxin-antitoxin system toxin | Toxin |
FJD32_RS07630 | 1675243..1675665 | - | 423 | WP_069455294.1 | type II toxin-antitoxin system antitoxin | Antitoxin |
FJD32_RS07635 | 1675772..1676539 | - | 768 | WP_086904479.1 | HutD family protein | - |
FJD32_RS07640 | 1676815..1677261 | - | 447 | WP_181159904.1 | copper resistance protein NlpE | - |
FJD32_RS07645 | 1677652..1679013 | + | 1362 | WP_109277866.1 | GAF domain-containing sensor histidine kinase | - |
FJD32_RS07650 | 1679157..1680047 | + | 891 | WP_055646646.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
FJD32_RS07655 | 1680034..1680576 | + | 543 | WP_037428279.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15296.57 Da Isoelectric Point: 6.3185
>T139450 WP_069455295.1 NZ_CP043902:c1675250-1674849 [Shewanella sp. LC6]
MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNN
LITQPLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNN
LITQPLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
Download Length: 402 bp
>T139450 NZ_CP058682:4569882-4570169 [Escherichia coli]
ATTAGGAATTTAAATCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAA
GGATATGAATAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACC
CGCTGCAAGGTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAA
CTTTTACGATTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
ATTAGGAATTTAAATCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAA
GGATATGAATAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACC
CGCTGCAAGGTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAA
CTTTTACGATTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
Antitoxin
Download Length: 141 a.a. Molecular weight: 15795.88 Da Isoelectric Point: 5.1520
>AT139450 WP_069455294.1 NZ_CP043902:c1675665-1675243 [Shewanella sp. LC6]
MQQLNEKKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSAST
VLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKDHRGSHFE
MQQLNEKKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSAST
VLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKDHRGSHFE
Download Length: 423 bp
>AT139450 NZ_CP058682:4569634-4569894 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A252EQR5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A501X4H4 |