Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1618102..1618933 Replicon chromosome
Accession NZ_CP043902
Organism Shewanella sp. LC6

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag FJD32_RS07295 Protein ID WP_088585313.1
Coordinates 1618102..1618518 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag FJD32_RS07300 Protein ID WP_140907854.1
Coordinates 1618511..1618933 (-) Length 141 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJD32_RS07285 1614310..1616250 + 1941 WP_140907858.1 polysaccharide biosynthesis protein -
FJD32_RS07290 1616354..1617706 + 1353 WP_140907853.1 phosphoglucosamine mutase -
FJD32_RS07295 1618102..1618518 - 417 WP_088585313.1 DUF86 domain-containing protein Toxin
FJD32_RS07300 1618511..1618933 - 423 WP_140907854.1 nucleotidyltransferase domain-containing protein Antitoxin
FJD32_RS07305 1619341..1619601 + 261 WP_055647496.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
FJD32_RS07310 1619603..1619950 + 348 WP_055647497.1 type II toxin-antitoxin system RelE/ParE family toxin -
FJD32_RS07315 1620162..1621370 + 1209 WP_140907855.1 molecular chaperone DnaJ -
FJD32_RS07320 1621490..1621696 - 207 WP_014610942.1 hypothetical protein -
FJD32_RS07325 1622164..1622580 - 417 WP_126512853.1 type II toxin-antitoxin system YafO family toxin -
FJD32_RS07330 1622592..1622885 - 294 WP_086904668.1 antitoxin of toxin-antitoxin stability system -
FJD32_RS07335 1622961..1623179 + 219 WP_088585318.1 transposase -
FJD32_RS07340 1623183..1623617 + 435 WP_088585319.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(12-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(9-96)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16056.55 Da        Isoelectric Point: 7.3244

>T139448 WP_088585313.1 NZ_CP043902:c1618518-1618102 [Shewanella sp. LC6]
MNDIIINKIATIKRCIKRIQQVYGDGSMFKQDFTLQDSVILNLQRCCEASIDIANHINRQQQLGIPQSSRDSFTLLSQNK
IINQQLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIEVIKFCPRMSY

Download         Length: 417 bp

>T139448 NZ_CP058682:4321561-4321779 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 141 a.a.        Molecular weight: 15889.94 Da        Isoelectric Point: 5.1231

>AT139448 WP_140907854.1 NZ_CP043902:c1618933-1618511 [Shewanella sp. LC6]
MQQLNESIIINLLQDNIPQLRLIYLFGSYAQGTQHRNSDIDIAVLADVTLDNIARWQLAQKLASVLDTDVDLVDLRTAST
VLCQQVVTQGKRLWGTRQDDEIFAVKTISMYQHLQAERQAIIDDATAKTTANDHRGRHFE

Download         Length: 423 bp

>AT139448 NZ_CP058682:4321161-4321535 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGCAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References