Detailed information of TA system TA139423

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1637678..1638206
• Replicon: chromosome
• Accession: NZ_CP043869
• Organism: Neptunomonas concharum strain JCM17730

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: F0U83_RS07680
• Protein ID: WP_138987211.1
• Coordinates: 1637678..1637965 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: F0U83_RS07685
• Protein ID: WP_138987212.1
• Coordinates: 1637955..1638206 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F0U83_RS07650	1632958..1634637	-	1680	WP_138987205.1	SufS family cysteine desulfurase	-
F0U83_RS07655	1634630..1635031	-	402	WP_138987206.1	DUF2069 domain-containing protein	-
F0U83_RS07660	1635031..1635630	-	600	WP_138987207.1	NAD(P)H:quinone oxidoreductase	-
F0U83_RS07665	1635631..1635981	-	351	WP_138987208.1	arsenate reductase (glutaredoxin)	-
F0U83_RS07670	1636089..1637309	+	1221	WP_138987209.1	YihY family inner membrane protein	-
F0U83_RS07675	1637334..1637612	+	279	WP_138987210.1	acylphosphatase	-
F0U83_RS07680	1637678..1637965	-	288	WP_138987211.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
F0U83_RS07685	1637955..1638206	-	252	WP_138987212.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
F0U83_RS07690	1638541..1639338	-	798	WP_170221773.1	signal peptidase I	-
F0U83_RS07695	1639537..1639809	+	273	WP_138987214.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
F0U83_RS07700	1639790..1640062	+	273	WP_138987215.1	Txe/YoeB family addiction module toxin	-
F0U83_RS07705	1640570..1640755	-	186	WP_138987216.1	hypothetical protein	-
F0U83_RS07710	1640836..1641360	-	525	WP_138987217.1	hypothetical protein	-
F0U83_RS07715	1641519..1642340	-	822	WP_138987218.1	hypothetical protein	-
F0U83_RS07720	1642647..1642985	-	339	WP_138987219.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-69)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11046.05 Da
• Isoelectric Point: 10.4934

>T139423 WP_138987211.1 NZ_CP043869:c1637965-1637678 [Neptunomonas concharum]
MTYKLKFLPAAQKEWSKLAPLIQSQFKKKLKERLENPHVPSSKLRGYDSVYKIKLRTAGYRLAYEVIDDEIIVYVLAIGK
RDKDAAYKKLASRIT

Nucleotide

• Length: 288 bp

>T139423 NZ_CP058671:3305687-3306103 [Salmonella enterica]
ATGAGTAAAACCTACATGCTGGATACCTGCATCTGTTCTTTCATTATGCGCGAACAGCCGGAAGCTGTGCTGAAACGCCT
TGAGCAGGCAGTGCTGCGCCGCCATCGTATTGTGGTGTCGGCGATTACCTACGCCGAAATGCGTTTTGGCTGTACGGGCA
AAAAGGCCTCGCCGCGCCATGCCCAACTGGTTGATGCATTCTGTAGTCGCCTGGATGCCGTGCTGGCCTGGGACCGGGCG
GCAGTGGATGCCACCACAGAGATCCGTGCCGTACTGGCCGCCGCCGGTACGCCGATTGGATCAAACGATGCGGCTATCGC
CGGCCATGCCATTGCGTCCGGGGCGATACTGGTCACTAATAACGTGAGGGAGTTTGAGCGGGTACCGGGTTTGCAGTACG
AAGATTGGGTAAAATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9103.29 Da
• Isoelectric Point: 3.9840

>AT139423 WP_138987212.1 NZ_CP043869:c1638206-1637955 [Neptunomonas concharum]
MRQVLADCSASISELKKNPTALLNEADGSAIAILNHNKPAAYLVPAETYELLIEMLDDYELAKLVESRRGDLSEAVEVDI
DDL

Nucleotide

• Length: 252 bp

>AT139423 NZ_CP058671:3305460-3305690 [Salmonella enterica]
ATGCGAACCGTATCTGTATTTAAAAATGGCAATAACCGCGCGATCCGCCTTCCACGCGATCTGGATTTTGACGGCGTCAA
CGAACTTGAAATCTTCCGCGAAGGCGACACGATTATACTGCGCCCCGCCCGCCCTTCCTGGGGATCATTCCGTCATGAGG
AAAAAGCCAGCCCAGACTTTCTGACGGAACGCGAAGACATCATCAGCGATGAGGGACGCTTTGAACTATGA