Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1562597..1563113 Replicon chromosome
Accession NZ_CP043869
Organism Neptunomonas concharum strain JCM17730

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag F0U83_RS07305 Protein ID WP_170221883.1
Coordinates 1562844..1563113 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag F0U83_RS07300 Protein ID WP_138988352.1
Coordinates 1562597..1562851 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0U83_RS07275 1557824..1558963 + 1140 WP_138988357.1 DUF4935 domain-containing protein -
F0U83_RS07280 1559125..1560837 + 1713 WP_138988356.1 hypothetical protein -
F0U83_RS07285 1560850..1561362 + 513 WP_138988355.1 hypothetical protein -
F0U83_RS07290 1561378..1561929 + 552 WP_138988354.1 hypothetical protein -
F0U83_RS07295 1561926..1562348 + 423 WP_170221885.1 NUDIX domain-containing protein -
F0U83_RS07300 1562597..1562851 + 255 WP_138988352.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F0U83_RS07305 1562844..1563113 + 270 WP_170221883.1 Txe/YoeB family addiction module toxin Toxin
F0U83_RS07310 1563339..1563629 - 291 WP_138988350.1 type II toxin-antitoxin system RelE/ParE family toxin -
F0U83_RS07315 1563622..1563843 - 222 WP_012518669.1 hypothetical protein -
F0U83_RS16955 1564043..1564189 + 147 WP_170221881.1 hypothetical protein -
F0U83_RS07320 1564446..1564838 + 393 WP_138988349.1 GFA family protein -
F0U83_RS07325 1564835..1565398 + 564 WP_138988348.1 Crp/Fnr family transcriptional regulator -
F0U83_RS07330 1565468..1565986 + 519 WP_138988347.1 DUF1772 domain-containing protein -
F0U83_RS07335 1566075..1566473 - 399 WP_138988346.1 VOC family protein -
F0U83_RS07340 1566553..1567416 - 864 WP_138988345.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(10-89)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10605.95 Da        Isoelectric Point: 7.9757

>T139422 WP_170221883.1 NZ_CP043869:1562844-1563113 [Neptunomonas concharum]
MSSSQYLLSWTDAAWDDYLYWQTQDKKTLKRINKLINDVRRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDDQAI
TIISCRYHY

Download         Length: 270 bp

>T139422 NZ_CP058671:c3215233-3214946 [Salmonella enterica]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCAGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCCCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9441.59 Da        Isoelectric Point: 5.0622

>AT139422 WP_138988352.1 NZ_CP043869:1562597-1562851 [Neptunomonas concharum]
MKIVSFTEARNSLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPQNAEHLNRSIAQYRAGKTTARE
LVDE

Download         Length: 255 bp

>AT139422 NZ_CP058671:c3214959-3214657 [Salmonella enterica]
ATGAGCATGGTTAAACATAAACGCGGCAACGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGTGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References