Detailed information of TA system TA139421

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 1473428..1473975
• Replicon: chromosome
• Accession: NZ_CP043869
• Organism: Neptunomonas concharum strain JCM17730

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: F0U83_RS06845
• Protein ID: WP_138988432.1
• Coordinates: 1473673..1473975 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: F0U83_RS06840
• Protein ID: WP_138988433.1
• Coordinates: 1473428..1473685 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F0U83_RS06805	1469234..1470100	+	867	WP_138988440.1	hypothetical protein	-
F0U83_RS06810	1470186..1470638	+	453	WP_138988439.1	hypothetical protein	-
F0U83_RS06815	1470703..1471443	+	741	WP_138988438.1	hypothetical protein	-
F0U83_RS06820	1471481..1471849	+	369	WP_138988437.1	hypothetical protein	-
F0U83_RS06825	1471932..1472354	+	423	WP_138988436.1	hypothetical protein	-
F0U83_RS06830	1472380..1472838	+	459	WP_138988435.1	hypothetical protein	-
F0U83_RS06835	1472899..1473270	+	372	WP_138988434.1	hypothetical protein	-
F0U83_RS06840	1473428..1473685	+	258	WP_138988433.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
F0U83_RS06845	1473673..1473975	+	303	WP_138988432.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
F0U83_RS06855	1474205..1474462	+	258	WP_211343697.1	transposase	-
F0U83_RS06860	1475133..1475921	+	789	WP_138988431.1	DUF2071 domain-containing protein	-
F0U83_RS06865	1475999..1476436	+	438	WP_138988430.1	hypothetical protein	-
F0U83_RS06870	1476488..1476781	+	294	WP_138988429.1	hypothetical protein	-
F0U83_RS06875	1476855..1477745	+	891	WP_138988428.1	M23 family metallopeptidase	-
F0U83_RS06880	1478000..1478389	+	390	WP_138988427.1	VOC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	1469234..1476436	7202

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-66)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11729.58 Da
• Isoelectric Point: 4.8951

>T139421 WP_138988432.1 NZ_CP043869:1473673-1473975 [Neptunomonas concharum]
MAEIIWTEPALSDLNDIAEYIALENAVAAKQWVQTIFSKVERLETFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRVERDLRKFLLSKQ

Nucleotide

• Length: 303 bp

>T139421 NZ_CP058671:2783361-2783588 [Salmonella enterica]
ATGACCACCTATTACTCACGCATTCCCAGCCTGCATCTCAAGGGTGACTGGCTGACAGAAGCGGGATTTGATACCGGCGC
GAGCGTGACAGTGAAGATCTCCGAGGGGTGTTTGATCCTGATTGCAGAGACGGACGAAGTGAGGGATTTACGGAAGGAGC
TTTATCAGGTGAAAAAGTCGATGAAGCATATTAAGGCGGGGGTAAATAATGTGGTGAACGGGAATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9618.10 Da
• Isoelectric Point: 6.7273

>AT139421 WP_138988433.1 NZ_CP043869:1473428-1473685 [Neptunomonas concharum]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYESMQNRLVILEGIARGERALADSKVVSHDEAKEKM
SKWLK

Nucleotide

• Length: 258 bp

>AT139421 NZ_CP058671:c2783578-2783327 [Salmonella enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAAATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACTGTCACGCTCGCGCCGGTATCAAATCCCGCTT
CTGTCAGCCAGTCACCCTTGAGATGCAGGCTGGGAATGCGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTCTCGTGG
CGGACGCTGACG