Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2064386..2064620 | Replicon | chromosome |
| Accession | NZ_CP043825 | ||
| Organism | Escherichia coli strain RM8082 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2064387..2064490 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2064386..2064620 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F1745_RS10440 | 2061298..2062386 | + | 1089 | WP_047088016.1 | RecT family recombinase | - |
| F1745_RS10445 | 2062450..2062644 | + | 195 | WP_021500490.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| F1745_RS10450 | 2062637..2062825 | + | 189 | WP_047087971.1 | DUF1187 family protein | - |
| - | 2062643..2062821 | - | 179 | NuclAT_0 | - | - |
| - | 2062643..2062821 | - | 179 | NuclAT_0 | - | - |
| - | 2062643..2062821 | - | 179 | NuclAT_0 | - | - |
| - | 2062643..2062821 | - | 179 | NuclAT_0 | - | - |
| F1745_RS10455 | 2062932..2063213 | + | 282 | WP_001311878.1 | excisionase | - |
| F1745_RS10460 | 2063179..2064255 | + | 1077 | WP_047087972.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2064386..2064620 | + | 235 | - | - | Antitoxin |
| - | 2064387..2064490 | - | 104 | - | - | Toxin |
| F1745_RS10465 | 2064648..2064989 | - | 342 | WP_000976472.1 | YebY family protein | - |
| F1745_RS10470 | 2065002..2065874 | - | 873 | WP_000879282.1 | copper homeostasis membrane protein CopD | - |
| F1745_RS10475 | 2065878..2066252 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| F1745_RS10480 | 2066391..2066621 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| F1745_RS10485 | 2066723..2067379 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| F1745_RS10490 | 2067403..2068065 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2006504..2086638 | 80134 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T139301 NZ_CP043825:c2064490-2064387 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT139301 NZ_CP043825:2064386-2064620 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
