Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3096716..3097365 Replicon chromosome
Accession NZ_CP043808
Organism Serinicoccus marinus DSM 15273

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FU792_RS14935 Protein ID WP_022925783.1
Coordinates 3096967..3097365 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FU792_RS14930 Protein ID WP_022925782.1
Coordinates 3096716..3096970 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FU792_RS14905 3091993..3092496 - 504 WP_022925777.1 hypothetical protein -
FU792_RS14910 3092506..3094464 - 1959 WP_022925778.1 DNA/RNA non-specific endonuclease -
FU792_RS14915 3094464..3094781 - 318 WP_022925779.1 hypothetical protein -
FU792_RS14920 3094816..3095238 - 423 WP_022925780.1 hypothetical protein -
FU792_RS14925 3095355..3096643 + 1289 Protein_2955 NupC/NupG family nucleoside CNT transporter -
FU792_RS14930 3096716..3096970 + 255 WP_022925782.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FU792_RS14935 3096967..3097365 + 399 WP_022925783.1 type II toxin-antitoxin system VapC family toxin Toxin
FU792_RS14940 3097391..3098379 + 989 Protein_2958 NAD(P)H-quinone oxidoreductase -
FU792_RS14945 3099400..3100413 - 1014 WP_022925786.1 hypothetical protein -
FU792_RS14950 3100437..3100949 - 513 WP_022925787.1 NUDIX hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14036.02 Da        Isoelectric Point: 4.8486

>T139244 WP_022925783.1 NZ_CP043808:3096967-3097365 [Serinicoccus marinus DSM 15273]
VTIVLDTSAVAAVIFGEPDAETLLRVMQRAAGDLLMSAATSVEVGIVVETRQGREATQDLRLLLDRLGVDIAPLDAAQAS
IAVDAWRRFGKGRHPASLNLGDCFAYAAAQRRDAPLLFKGGDFAQTDVRSAL

Download         Length: 399 bp

>T139244 NZ_CP058596:c675773-675309 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGATGCTTTAGTTGC
CGAAGTCGAGGCATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGCGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGTAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAGCCATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9129.24 Da        Isoelectric Point: 4.5749

>AT139244 WP_022925782.1 NZ_CP043808:3096716-3096970 [Serinicoccus marinus DSM 15273]
MALNIKDAETDRLARELADATGESITVAARRAIEERLARVTALARAEKGTDELEGIIDRGRRRPVIDARTPEDIVGYDEA
GLPG

Download         Length: 255 bp

>AT139244 NZ_CP058596:c676108-675773 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTAACGCTGTACTGACCACTGAATCAAAGGTCACTATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCTGGCCTGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCGACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGACGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References