Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1416948..1417543 Replicon chromosome
Accession NZ_CP043808
Organism Serinicoccus marinus DSM 15273

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FU792_RS06590 Protein ID WP_202804717.1
Coordinates 1416948..1417250 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FU792_RS06595 Protein ID WP_022923717.1
Coordinates 1417247..1417543 (+) Length 99 a.a.

Genomic Context

FU792_RS06560FU792_RS06565FU792_RS06570FU792_RS06575FU792_RS06590FU792_RS06595FU792_RS06600FU792_RS06610FU792_RS06580FU792_RS06585FU792_RS06605FU792_RS06615
Location: 1411952..1412149 (198 bp)
Type: Others
Protein ID: WP_022923711.1
Location: 1413141..1414157 (1017 bp)
Type: Others
Protein ID: WP_022923712.1
Location: 1414173..1414838 (666 bp)
Type: Others
Protein ID: WP_022923713.1
Location: 1414960..1415499 (540 bp)
Type: Others
Protein ID: WP_022923714.1
Location: 1416948..1417250 (303 bp)
Type: Toxin
Protein ID: WP_202804717.1
Location: 1417247..1417543 (297 bp)
Type: Antitoxin
Protein ID: WP_022923717.1
Location: 1417714..1418295 (582 bp)
Type: Others
Protein ID: WP_028130777.1
Location: 1419426..1420265 (840 bp)
Type: Others
Protein ID: WP_149814637.1
Location: 1415696..1415818 (123 bp)
Type: Others
Protein ID: Protein_1316
Location: 1415853..1416782 (930 bp)
Type: Others
Protein ID: WP_022923715.1
Location: 1418525..1419016 (492 bp)
Type: Others
Protein ID: WP_161600213.1
Location: 1420994..1421749 (756 bp)
Type: Others
Protein ID: WP_149814638.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FU792_RS065601411952..1412149+198WP_022923711.1hypothetical protein-
FU792_RS065651413141..1414157+1017WP_022923712.1oxidoreductase-
FU792_RS065701414173..1414838+666WP_022923713.1hypothetical protein-
FU792_RS065751414960..1415499+540WP_022923714.1DUF1697 domain-containing protein-
FU792_RS065801415696..1415818-123Protein_1316toxin-antitoxin system HicB family antitoxin-
FU792_RS065851415853..1416782-930WP_022923715.1tyrosine-type recombinase/integrase-
FU792_RS065901416948..1417250+303WP_202804717.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FU792_RS065951417247..1417543+297WP_022923717.1putative addiction module antidote proteinAntitoxin
FU792_RS066001417714..1418295+582WP_028130777.1AAA family ATPase-
FU792_RS066051418525..1419016-492WP_161600213.1SRPBCC domain-containing protein-
FU792_RS066101419426..1420265+840WP_149814637.1hypothetical protein-
FU792_RS066151420994..1421749-756WP_149814638.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-86)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-92)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11259.82 Da        Isoelectric Point: 10.3079

>T139237 WP_202804717.1 NZ_CP043808:1416948-1417250 [Serinicoccus marinus DSM 15273]
VEVVRSGTFDWWLTRLKDKRAAARVLVRIDRLAAGNPGDVKPVGQGVSEMRINYGPGYRVYYLSHGDQIVLLLTGGDKST
QEADIRKAHEVAAEWRKHRS

Download         Length: 303 bp

>T139237 NZ_CP058575:54550-54855 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCTGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGTTGTCAGATAAGGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAGGAAGTG
GCTGATCTCAGCCACCGAGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10466.85 Da        Isoelectric Point: 4.5515

>AT139237 WP_022923717.1 NZ_CP043808:1417247-1417543 [Serinicoccus marinus DSM 15273]
MTNETFAPFDNADYLNTFEDVAAYLEAVMEVAEDDPKVIAAALGAIARSRNLSQIARQAGMSREGLYKALSADGNPSLAT
VVKVAHALGLRLHFEAIA

Download         Length: 297 bp

>AT139237 NZ_CP058575:54330-54548 [Escherichia coli]
ATGAAGCAGCGCATTACAGTCACCGTCGACAGTGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGGCT
GGTAAGCACCACCCTGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCAGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References