Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 716220..716896 Replicon chromosome
Accession NZ_CP043808
Organism Serinicoccus marinus DSM 15273

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FU792_RS03525 Protein ID WP_022924335.1
Coordinates 716468..716896 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FU792_RS03520 Protein ID WP_022924336.1
Coordinates 716220..716471 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FU792_RS03495 711685..712551 - 867 WP_022924341.1 ketol-acid reductoisomerase -
FU792_RS03500 712842..713942 + 1101 WP_022924340.1 branched-chain amino acid aminotransferase -
FU792_RS03505 713991..714872 - 882 WP_022924339.1 hypothetical protein -
FU792_RS03510 715051..715377 + 327 WP_028130895.1 multidrug efflux SMR transporter -
FU792_RS03515 715409..716188 + 780 WP_022924337.1 fumarylacetoacetate hydrolase family protein -
FU792_RS03520 716220..716471 + 252 WP_022924336.1 antitoxin Antitoxin
FU792_RS03525 716468..716896 + 429 WP_022924335.1 PIN domain-containing protein Toxin
FU792_RS03530 716910..717737 + 828 WP_022924334.1 glutamate racemase -
FU792_RS03535 717731..718108 - 378 WP_022924333.1 PIN domain-containing protein -
FU792_RS03540 718105..718356 - 252 WP_022924332.1 ribbon-helix-helix protein, CopG family -
FU792_RS03545 718487..719743 + 1257 WP_202980400.1 inorganic phosphate transporter -
FU792_RS17275 719740..720057 + 318 WP_202980401.1 hypothetical protein -
FU792_RS03550 720198..721610 + 1413 WP_022924330.1 hemolysin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-133)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15430.58 Da        Isoelectric Point: 5.1211

>T139235 WP_022924335.1 NZ_CP043808:716468-716896 [Serinicoccus marinus DSM 15273]
MIVPDVNVLLYAHVDAFPEHDRARTWWEETLSAGRPVGLAPVVVFGFIRIATSRRVLTRPFSVQQAQAVVESWLAQPGVQ
MLDSGREHLGRTLEVLTGVGTAAALTMDAQIAAHAFIEGAAVATHDTDFGRFADLDVVDPVR

Download         Length: 429 bp

>T139235 NZ_CP058574:4359594-4359851 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9504.78 Da        Isoelectric Point: 6.8803

>AT139235 WP_022924336.1 NZ_CP043808:716220-716471 [Serinicoccus marinus DSM 15273]
MRTTLTLDADVVRLLEQAVHDRRTSMKSVVNDALRQALRPAQAPRPYRVDVHHSELVVGVDPARLNQLADELEDETIVDK
RHR

Download         Length: 252 bp

>AT139235 NZ_CP058574:4359863-4360408 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References