Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 4036420..4037143 Replicon chromosome
Accession NZ_CP043727
Organism Yersinia canariae strain NCTC 14382

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag F0T03_RS18515 Protein ID WP_159679994.1
Coordinates 4036420..4036740 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag F0T03_RS18520 Protein ID WP_159681006.1
Coordinates 4036808..4037143 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0T03_RS18500 4033248..4035086 + 1839 WP_145554005.1 RNA polymerase sigma factor RpoD -
F0T03_RS18510 4035473..4036306 - 834 WP_159679992.1 DUF4942 domain-containing protein -
F0T03_RS18515 4036420..4036740 - 321 WP_159679994.1 TA system toxin CbtA family protein Toxin
F0T03_RS18520 4036808..4037143 - 336 WP_159681006.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
F0T03_RS18525 4037157..4037636 - 480 WP_159679996.1 DNA repair protein RadC -
F0T03_RS18530 4038074..4038997 - 924 WP_159679998.1 cation diffusion facilitator family transporter -
F0T03_RS18535 4039197..4039769 - 573 WP_159680001.1 cytochrome b/b6 domain-containing protein -
F0T03_RS18540 4040581..4040979 - 399 WP_099462567.1 hypothetical protein -
F0T03_RS18545 4041047..4041484 - 438 WP_159680003.1 hypothetical protein -
F0T03_RS18550 4041535..4042071 - 537 WP_159680005.1 DUF4339 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(6-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12014.65 Da        Isoelectric Point: 5.0359

>T139189 WP_159679994.1 NZ_CP043727:c4036740-4036420 [Yersinia canariae]
MQTSTVPATLPVSSRLSPVQVWQQLLTYLLEQHYGLTLNDTPFHEDAAIQEHIEAGITLADAVNFLVERYELIRTDRKGF
TWQEQAPFLTATDILRAKRATGLMNT

Download         Length: 321 bp

>T139189 NZ_CP058551:c23880-23575 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCTGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12602.30 Da        Isoelectric Point: 5.4916

>AT139189 WP_159681006.1 NZ_CP043727:c4037143-4036808 [Yersinia canariae]
MNKDATQTWGLKRDITPCFGALLVQEGHRLHFLADRAEFNGSFSEMQTRDLDEAFPHFVVHMELMLLSGELNPRCAHCVT
LYRNGLTCEADTLGSYGYVYIAIYPSNQVKD

Download         Length: 336 bp

>AT139189 NZ_CP058551:c24100-23882 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGTGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References