Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3738962..3739634 Replicon chromosome
Accession NZ_CP043727
Organism Yersinia canariae strain NCTC 14382

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag F0T03_RS17225 Protein ID WP_145553097.1
Coordinates 3738962..3739387 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag F0T03_RS17230 Protein ID WP_145553098.1
Coordinates 3739368..3739634 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0T03_RS17205 3734737..3735255 + 519 WP_145553089.1 flavodoxin FldB -
F0T03_RS17210 3735312..3736733 - 1422 WP_159679679.1 cell envelope integrity protein CreD -
F0T03_RS17215 3736826..3738253 - 1428 WP_159679681.1 two-component system sensor histidine kinase CreC -
F0T03_RS17220 3738264..3738962 - 699 WP_145553095.1 two-component system response regulator CreB -
F0T03_RS17225 3738962..3739387 - 426 WP_145553097.1 protein YgfX Toxin
F0T03_RS17230 3739368..3739634 - 267 WP_145553098.1 FAD assembly factor SdhE Antitoxin
F0T03_RS17235 3740021..3741013 + 993 WP_145553100.1 tRNA-modifying protein YgfZ -
F0T03_RS17240 3741129..3741818 - 690 WP_145553102.1 hemolysin III family protein -
F0T03_RS17245 3742138..3742740 + 603 WP_145553104.1 HD domain-containing protein -
F0T03_RS17250 3742742..3743491 - 750 WP_159679684.1 SDR family oxidoreductase -
F0T03_RS17255 3743507..3743944 - 438 WP_159680962.1 lipocalin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16406.27 Da        Isoelectric Point: 9.3669

>T139188 WP_145553097.1 NZ_CP043727:c3739387-3738962 [Yersinia canariae]
VAQWRCDLRISWHTQLFSLLAHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNITSCQGEIRLKPGNVVLWKRH
EWIVIKQPWMTPYGVLLSLQQTSSRSTRKRLWLAADSMSEEEWRQLCLLLRHSFGPDEGIN

Download         Length: 426 bp

>T139188 NZ_CP058550:73749-74054 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGATGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10500.02 Da        Isoelectric Point: 5.5730

>AT139188 WP_145553098.1 NZ_CP043727:c3739634-3739368 [Yersinia canariae]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQVFIRLLECDDPDLFNWLMNHGEPQDSELRHMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT139188 NZ_CP058550:73529-73747 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References