Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 4162462..4162969 Replicon chromosome
Accession NZ_CP043641
Organism Leifsonia shinshuensis strain INR9

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag F1C12_RS20265 Protein ID WP_185276609.1
Coordinates 4162462..4162728 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag F1C12_RS20270 Protein ID WP_185276610.1
Coordinates 4162721..4162969 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1C12_RS20235 4157936..4159195 + 1260 WP_185279091.1 chloride channel protein -
F1C12_RS20240 4159339..4160652 + 1314 WP_185276605.1 S1C family serine protease -
F1C12_RS20245 4160831..4161121 + 291 WP_185276606.1 DUF4190 domain-containing protein -
F1C12_RS20250 4161263..4161829 + 567 WP_185276607.1 hypothetical protein -
F1C12_RS20260 4161991..4162443 - 453 WP_185276608.1 hypothetical protein -
F1C12_RS20265 4162462..4162728 - 267 WP_185276609.1 Txe/YoeB family addiction module toxin Toxin
F1C12_RS20270 4162721..4162969 - 249 WP_185276610.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F1C12_RS20275 4163196..4167137 - 3942 WP_185276611.1 helix-turn-helix domain-containing protein -
F1C12_RS20280 4167203..4167562 - 360 WP_185276612.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10388.74 Da        Isoelectric Point: 6.4649

>T139175 WP_185276609.1 NZ_CP043641:c4162728-4162462 [Leifsonia shinshuensis]
VSDRKLAWTAGGWEDYLYWQGQDRRTLKRINLLIEDILRDDPFDGVGKPEPLKHALAGAWSRRIDEANRLVYLVDDNYVI
VLQARYHY

Download         Length: 267 bp

>T139175 NZ_CP058548:c1365438-1365097 [Klebsiella pneumoniae]
ATGAAAACTCTACCTGCTATAATTTCGCGGGCGGCGAAGCCCTGTCTGTCGCCCGTTGCAGTCTGGCAAATGCTACTTAC
ACGCCTGCTGGAAAAACACTATGGTCTGACCCTGAACGATACGCCGTTCTGTGATGAAACCGTTATACAGGAACATATCG
ATGCCGGTATTACGCTGGCTGATGCCGTTAATTTTCTGGTGGAAAAATACGGACTGGTTCGTATCGACAGGAATGGATTT
GTCTGGCAGGAACAATCACCTTATCTTCGGGCCGTTGATATTCTGCGAGCGCGGCAGGCAACTGGCTTATTGCGACAAAG
CCGTAACAACGCAATACGTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9129.19 Da        Isoelectric Point: 4.3766

>AT139175 WP_185276610.1 NZ_CP043641:c4162969-4162721 [Leifsonia shinshuensis]
MAITASEARSDLFGLIERVNLDQTEVEITSKRGSAVLMSKDEYDSLLETTYLLRSPKNARRLIDAIESARAGDITEHDLT
SE

Download         Length: 249 bp

>AT139175 NZ_CP058548:c1365776-1365459 [Klebsiella pneumoniae]
ATGAGCAACATTACATGGGGCCTGCAGCGGGATACCACGCCGCGTCTGGGAGCCCGTCTGGTACAGGAGGGGAACCAACT
GCATTATCTGGCTGACCGGGCCAGTATGACCGGTAAATTCAGTGACGCCGAATGCCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCAGCCAGATGGAATCGATGCTGATCACTGGTGAAATGAATCCTCGCCATGCCCACTGTGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACCCTTGGCAGTTGCGGCTACGTATACATCGCCGTTTACCCCATCCAACGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References