Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 4162462..4162969 Replicon chromosome
Accession NZ_CP043641
Organism Leifsonia shinshuensis strain INR9

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag F1C12_RS20265 Protein ID WP_185276609.1
Coordinates 4162462..4162728 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag F1C12_RS20270 Protein ID WP_185276610.1
Coordinates 4162721..4162969 (-) Length 83 a.a.

Genomic Context

F1C12_RS20235F1C12_RS20240F1C12_RS20245F1C12_RS20250F1C12_RS20260F1C12_RS20265F1C12_RS20270F1C12_RS20275F1C12_RS20280
Location: 4157936..4159195 (1260 bp)
Type: Others
Protein ID: WP_185279091.1
Location: 4159339..4160652 (1314 bp)
Type: Others
Protein ID: WP_185276605.1
Location: 4160831..4161121 (291 bp)
Type: Others
Protein ID: WP_185276606.1
Location: 4161263..4161829 (567 bp)
Type: Others
Protein ID: WP_185276607.1
Location: 4161991..4162443 (453 bp)
Type: Others
Protein ID: WP_185276608.1
Location: 4162462..4162728 (267 bp)
Type: Toxin
Protein ID: WP_185276609.1
Location: 4162721..4162969 (249 bp)
Type: Antitoxin
Protein ID: WP_185276610.1
Location: 4163196..4167137 (3942 bp)
Type: Others
Protein ID: WP_185276611.1
Location: 4167203..4167562 (360 bp)
Type: Others
Protein ID: WP_185276612.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
F1C12_RS202354157936..4159195+1260WP_185279091.1chloride channel protein-
F1C12_RS202404159339..4160652+1314WP_185276605.1S1C family serine protease-
F1C12_RS202454160831..4161121+291WP_185276606.1DUF4190 domain-containing protein-
F1C12_RS202504161263..4161829+567WP_185276607.1hypothetical protein-
F1C12_RS202604161991..4162443-453WP_185276608.1hypothetical protein-
F1C12_RS202654162462..4162728-267WP_185276609.1Txe/YoeB family addiction module toxinToxin
F1C12_RS202704162721..4162969-249WP_185276610.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
F1C12_RS202754163196..4167137-3942WP_185276611.1helix-turn-helix domain-containing protein-
F1C12_RS202804167203..4167562-360WP_185276612.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10388.74 Da        Isoelectric Point: 6.4649

>T139175 WP_185276609.1 NZ_CP043641:c4162728-4162462 [Leifsonia shinshuensis]
VSDRKLAWTAGGWEDYLYWQGQDRRTLKRINLLIEDILRDDPFDGVGKPEPLKHALAGAWSRRIDEANRLVYLVDDNYVI
VLQARYHY

Download         Length: 267 bp

>T139175 NZ_CP058548:c1365438-1365097 [Klebsiella pneumoniae]
ATGAAAACTCTACCTGCTATAATTTCGCGGGCGGCGAAGCCCTGTCTGTCGCCCGTTGCAGTCTGGCAAATGCTACTTAC
ACGCCTGCTGGAAAAACACTATGGTCTGACCCTGAACGATACGCCGTTCTGTGATGAAACCGTTATACAGGAACATATCG
ATGCCGGTATTACGCTGGCTGATGCCGTTAATTTTCTGGTGGAAAAATACGGACTGGTTCGTATCGACAGGAATGGATTT
GTCTGGCAGGAACAATCACCTTATCTTCGGGCCGTTGATATTCTGCGAGCGCGGCAGGCAACTGGCTTATTGCGACAAAG
CCGTAACAACGCAATACGTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9129.19 Da        Isoelectric Point: 4.3766

>AT139175 WP_185276610.1 NZ_CP043641:c4162969-4162721 [Leifsonia shinshuensis]
MAITASEARSDLFGLIERVNLDQTEVEITSKRGSAVLMSKDEYDSLLETTYLLRSPKNARRLIDAIESARAGDITEHDLT
SE

Download         Length: 249 bp

>AT139175 NZ_CP058548:c1365776-1365459 [Klebsiella pneumoniae]
ATGAGCAACATTACATGGGGCCTGCAGCGGGATACCACGCCGCGTCTGGGAGCCCGTCTGGTACAGGAGGGGAACCAACT
GCATTATCTGGCTGACCGGGCCAGTATGACCGGTAAATTCAGTGACGCCGAATGCCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCAGCCAGATGGAATCGATGCTGATCACTGGTGAAATGAATCCTCGCCATGCCCACTGTGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACCCTTGGCAGTTGCGGCTACGTATACATCGCCGTTTACCCCATCCAACGATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References