Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 4346912..4347486 Replicon chromosome
Accession NZ_CP043626
Organism Pseudomonas denitrificans (nom. rej.) strain BG1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F1C79_RS20095 Protein ID WP_081520051.1
Coordinates 4346912..4347277 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F1C79_RS20100 Protein ID WP_151188412.1
Coordinates 4347271..4347486 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1C79_RS20080 4342535..4343512 + 978 WP_151188411.1 sigma-54-dependent transcriptional regulator -
F1C79_RS20085 4343581..4343916 - 336 WP_015478994.1 hypothetical protein -
F1C79_RS20090 4344689..4346647 + 1959 WP_139791660.1 choline BCCT transporter BetT -
F1C79_RS20095 4346912..4347277 - 366 WP_081520051.1 type II toxin-antitoxin system VapC family toxin Toxin
F1C79_RS20100 4347271..4347486 - 216 WP_151188412.1 ribbon-helix-helix protein, CopG family Antitoxin
F1C79_RS20105 4347620..4349659 - 2040 WP_081520345.1 oligopeptide transporter, OPT family -
F1C79_RS20110 4349896..4350732 - 837 WP_151188413.1 taurine dioxygenase -
F1C79_RS20115 4350818..4351636 - 819 WP_151188414.1 ABC transporter permease subunit -
F1C79_RS20120 4351626..4352429 - 804 WP_151188415.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-104)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-38)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13723.89 Da        Isoelectric Point: 5.8990

>T139158 WP_081520051.1 NZ_CP043626:c4347277-4346912 [Pseudomonas denitrificans (nom. rej.)]
MVKVLFDTNILIDYLNGHVQARDELALYSDRAISIITWMEVLIGATPQTEAATRAFLSSFTLLALDERIAQRAVEVRQRL
RVKLPDAVIKASAEVEGRLLVTRNVKDFDEREPGVRLPYQL

Download         Length: 366 bp

>T139158 NZ_CP058544:c207563-206646 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCAATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGCGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAGTCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8277.15 Da        Isoelectric Point: 4.1813

>AT139158 WP_151188412.1 NZ_CP043626:c4347486-4347271 [Pseudomonas denitrificans (nom. rej.)]
MRTLVDIPVEYLERLNDISERQQQSRASVIREAIAEYLVNHAQADADAAFGLWQENQVDGLAYQEKVREEW

Download         Length: 216 bp

>AT139158 NZ_CP058544:c208327-207569 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTGCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References