Detailed information of TA system TA139157

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 3828850..3829363
• Replicon: chromosome
• Accession: NZ_CP043626
• Organism: Pseudomonas denitrificans (nom. rej.) strain BG1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: F1C79_RS17690
• Protein ID: WP_081516089.1
• Coordinates: 3829079..3829363 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: F1C79_RS17685
• Protein ID: WP_151188162.1
• Coordinates: 3828850..3829089 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F1C79_RS17675	3825913..3827133	-	1221	WP_151188160.1	exonuclease subunit SbcD	-
F1C79_RS17680	3827371..3828732	+	1362	WP_151188161.1	ABC transporter substrate-binding protein	-
F1C79_RS17685	3828850..3829089	+	240	WP_151188162.1	ribbon-helix-helix protein, CopG family	Antitoxin
F1C79_RS17690	3829079..3829363	+	285	WP_081516089.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
F1C79_RS17695	3829476..3830483	+	1008	WP_081516091.1	nucleoid-associated protein YejK	-
F1C79_RS17700	3830570..3831478	-	909	WP_151188163.1	hypothetical protein	-
F1C79_RS17705	3831819..3832589	+	771	WP_151189730.1	hypothetical protein	-
F1C79_RS17710	3832570..3833505	-	936	WP_081516095.1	glutathione S-transferase family protein	-
F1C79_RS17715	3833569..3833874	-	306	WP_151188164.1	GIY-YIG nuclease family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10675.39 Da
• Isoelectric Point: 11.9435

>T139157 WP_081516089.1 NZ_CP043626:3829079-3829363 [Pseudomonas denitrificans (nom. rej.)]
MRIEWLRNALRNLDTEASYIAQDNPAAARAFVSAVLTDVALLAANPAAGREGRVPGTREWAMSSHPYLIPYRIRGGRLQV
LRIFHIRRLPPVRW

Nucleotide

• Length: 285 bp

>T139157 NZ_CP058544:c42332-42048 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8698.65 Da
• Isoelectric Point: 4.0941

>AT139157 WP_151188162.1 NZ_CP043626:3828850-3829089 [Pseudomonas denitrificans (nom. rej.)]
MPIMSLRLSDDQSETLAKLAEATGRSKNFLAAQALEEYLNRESWQIGEIQQAIAEADAGDFASDAEVKAILNKWARDAD

Nucleotide

• Length: 240 bp

>AT139157 NZ_CP058544:c42564-42322 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGACGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCAGGGGTTAAGGTGAGTCTGGATGACCTA
TGA