Detailed information of TA system TA139156

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 3521867..3523000
• Replicon: chromosome
• Accession: NZ_CP043626
• Organism: Pseudomonas denitrificans (nom. rej.) strain BG1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: F1C79_RS16010
• Protein ID: WP_081520192.1
• Coordinates: 3521867..3522631 (-)
• Length: 255 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: F1C79_RS16015
• Protein ID: WP_151187976.1
• Coordinates: 3522632..3523000 (-)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F1C79_RS15990	3517223..3518113	+	891	WP_151187973.1	metal-dependent hydrolase	-
F1C79_RS15995	3518202..3519548	+	1347	WP_151187974.1	FAD-binding oxidoreductase	-
F1C79_RS16000	3519645..3521009	-	1365	WP_167523294.1	DNA recombination protein RmuC	-
F1C79_RS16005	3521580..3521789	-	210	WP_139791670.1	hypothetical protein	-
F1C79_RS16010	3521867..3522631	-	765	WP_081520192.1	RES family NAD+ phosphorylase	Toxin
F1C79_RS16015	3522632..3523000	-	369	WP_151187976.1	DUF2384 domain-containing protein	Antitoxin
F1C79_RS16020	3523266..3523715	+	450	WP_151187977.1	RcnB family protein	-
F1C79_RS16025	3523722..3524165	-	444	WP_151187978.1	hypothetical protein	-
F1C79_RS16030	3524290..3524772	+	483	WP_151187979.1	GreA/GreB family elongation factor	-
F1C79_RS16035	3524916..3525263	+	348	WP_017522075.1	carboxymuconolactone decarboxylase family protein	-
F1C79_RS16040	3525362..3525730	+	369	WP_151187980.1	hypothetical protein	-
F1C79_RS16050	3526002..3526712	-	711	WP_045210340.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
F1C79_RS16055	3526742..3527452	-	711	WP_138215476.1	MBL fold metallo-hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (68-210)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 255 a.a.
• Molecular weight: 28841.06 Da
• Isoelectric Point: 8.4586

>T139156 WP_081520192.1 NZ_CP043626:c3522631-3521867 [Pseudomonas denitrificans (nom. rej.)]
MSFAAGARLWAKHEDSVIAPIRGRLVRLVESQGQVATLQLVDTLEEQALLEELLETSKPRMPPPAESLHYLLKTPFRYPP
LRWGSRFGRRHEPSLFYGALKLETAMAESAFYRFVLWEGMATPPPSGRILSEHASFEARFQVQKGVRLHLPPFREHEALL
DPQDYSVTQGLGSAMRDAGVEAFEYRSARCPQGGINVALFVPAAFTEKRPRNLMPWLCETTSEYVAFKHAQVPDSPRLYR
REQYLVDGRLPHPA

Nucleotide

• Length: 765 bp

>T139156 NZ_CP058533:3704564-3704854 [Pseudomonas fluorescens]
ATGAGCGAGTCCTTTACCCGCTTCGATGCGGCAAAATATCTGAAAACCCCTCTGGAGATGGCTGCATATTTAGAGACCTG
CTTTGAGGATGATGCTGGTGATGGTCTATTGATTCGTACCGCTCTCAACGATATCGCCCGCGCCCAAGGCATGACCCAAG
TAGCCCGCGACGCCGGCCTCGGAAGAGAAAGTCTATACAAAGCCCTCTCCAGCAATGGCAATCCCGAGTTCGCGACTATC
ATGAAAGTCATGAAGGCTTTGGGCCTCAAGCTTCACGCCACAGCGATCTGA

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13458.67 Da
• Isoelectric Point: 8.6262

>AT139156 WP_151187976.1 NZ_CP043626:c3523000-3522632 [Pseudomonas denitrificans (nom. rej.)]
MSALLKENPAADAVLAKAVLTAREHLAMTQQELAAIVGVDRSAVSRWKQNGLRVDSKTGELALLLVRIYRALFALFGGNH
EDMRHFLRTENRHLGGVPLELMEQVQGLVAVVEYLDAIRGKV

Nucleotide

• Length: 369 bp

>AT139156 NZ_CP058533:3704261-3704560 [Pseudomonas fluorescens]
ATTGAGTTCAATGAAACCACTGAGTTTGTCAAATGGTTGGAAGCAGTTCGGGACCCGTTCGTAAAAGTTCGCGTAATCAA
GAGAGTGCGAATGGCTGAAGCCGGAAATTTTGGTGACTGCGAGTCAGTGGGGGATAGCGTGTTTGAAATGCGGATCCATT
ACGGCCCAGGATATCGCGTTTACTTCACCCGCCGAGACGAGGTGGTTTATCTGTTGCTAATCGGCGGTGACAAATCAACA
CAGAGCAGAGACATCAAACGTGCAAAGCAAATCGCAATAAATTTTGGTAGCGAGGAATAA