Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 149644..150278 Replicon chromosome
Accession NZ_CP043626
Organism Pseudomonas denitrificans (nom. rej.) strain BG1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F1C79_RS00775 Protein ID WP_151186206.1
Coordinates 149644..150048 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F1C79_RS00780 Protein ID WP_151186207.1
Coordinates 150048..150278 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1C79_RS00755 145561..146649 - 1089 WP_151186204.1 phosphotransferase -
F1C79_RS00760 146786..147814 - 1029 WP_151186205.1 ABC transporter substrate-binding protein -
F1C79_RS00765 148148..148882 + 735 WP_045209895.1 SDR family oxidoreductase -
F1C79_RS00770 148955..149641 + 687 WP_081517765.1 GntR family transcriptional regulator -
F1C79_RS00775 149644..150048 - 405 WP_151186206.1 tRNA(fMet)-specific endonuclease VapC Toxin
F1C79_RS00780 150048..150278 - 231 WP_151186207.1 antitoxin Antitoxin
F1C79_RS00785 150482..151680 - 1199 Protein_157 CoA transferase -
F1C79_RS00790 151941..153119 + 1179 WP_081517767.1 GGDEF domain-containing protein -
F1C79_RS00795 153181..153720 + 540 WP_081517768.1 YaeQ family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-49)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14638.83 Da        Isoelectric Point: 6.8622

>T139155 WP_151186206.1 NZ_CP043626:c150048-149644 [Pseudomonas denitrificans (nom. rej.)]
MLKYLLDTNICIFTIKNKPEAVREAFNRHHGQLCISSVTLMELIYGAEKSSAPESNLAVVEGFAARLEVLSYDSGAAAHT
GQLRAELAKAGKPIGPYDQMIAGHARSLGLILVSNNLREFERVPGLRVEDWVSA

Download         Length: 405 bp

>T139155 NZ_CP058533:3704261-3704560 [Pseudomonas fluorescens]
ATTGAGTTCAATGAAACCACTGAGTTTGTCAAATGGTTGGAAGCAGTTCGGGACCCGTTCGTAAAAGTTCGCGTAATCAA
GAGAGTGCGAATGGCTGAAGCCGGAAATTTTGGTGACTGCGAGTCAGTGGGGGATAGCGTGTTTGAAATGCGGATCCATT
ACGGCCCAGGATATCGCGTTTACTTCACCCGCCGAGACGAGGTGGTTTATCTGTTGCTAATCGGCGGTGACAAATCAACA
CAGAGCAGAGACATCAAACGTGCAAAGCAAATCGCAATAAATTTTGGTAGCGAGGAATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8509.40 Da        Isoelectric Point: 4.2958

>AT139155 WP_151186207.1 NZ_CP043626:c150278-150048 [Pseudomonas denitrificans (nom. rej.)]
MEQGSVFQSNRSQAIRLPKAVALPEEVKRVDVVAVGRTRIITPAGEAWDSWFDGDNVSADFMSEREQPADQEREGF

Download         Length: 231 bp

>AT139155 NZ_CP058533:3704564-3704854 [Pseudomonas fluorescens]
ATGAGCGAGTCCTTTACCCGCTTCGATGCGGCAAAATATCTGAAAACCCCTCTGGAGATGGCTGCATATTTAGAGACCTG
CTTTGAGGATGATGCTGGTGATGGTCTATTGATTCGTACCGCTCTCAACGATATCGCCCGCGCCCAAGGCATGACCCAAG
TAGCCCGCGACGCCGGCCTCGGAAGAGAAAGTCTATACAAAGCCCTCTCCAGCAATGGCAATCCCGAGTTCGCGACTATC
ATGAAAGTCATGAAGGCTTTGGGCCTCAAGCTTCACGCCACAGCGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References