Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 3457666..3458172 Replicon chromosome
Accession NZ_CP043624
Organism Glutamicibacter sp. ZJUTW

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag F0M17_RS16205 Protein ID WP_149597786.1
Coordinates 3457918..3458172 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F0M17_RS16200 Protein ID WP_149597574.1
Coordinates 3457666..3457917 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0M17_RS16175 3452717..3453178 + 462 WP_038992873.1 DUF3817 domain-containing protein -
F0M17_RS16185 3453471..3455258 - 1788 WP_149597571.1 plasmid pRiA4b ORF-3 family protein -
F0M17_RS16190 3455462..3456160 + 699 WP_149597572.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
F0M17_RS16195 3456254..3457309 + 1056 WP_149597573.1 GTP-binding protein -
F0M17_RS16200 3457666..3457917 + 252 WP_149597574.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F0M17_RS16205 3457918..3458172 + 255 WP_149597786.1 Txe/YoeB family addiction module toxin Toxin
F0M17_RS16210 3458336..3458488 + 153 Protein_3171 DUF3375 family protein -
F0M17_RS16215 3458789..3459625 - 837 WP_149597575.1 (S)-ureidoglycine aminohydrolase -
F0M17_RS16220 3459636..3460889 - 1254 WP_149597576.1 aldolase -
F0M17_RS16225 3460886..3462517 - 1632 WP_073707129.1 malate synthase A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10084.57 Da        Isoelectric Point: 8.9482

>T139154 WP_149597786.1 NZ_CP043624:3457918-3458172 [Glutamicibacter sp. ZJUTW]
MRLVWDRAGWDDYVHWQTAHRRVLKRVNTLIEACLRDPFQGIGKPEQLKFGASGSWSRRITDEHRLVYIVIEEDLIILQA
RYQY

Download         Length: 255 bp

>T139154 NZ_CP058527:480376-480759 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9432.48 Da        Isoelectric Point: 4.4805

>AT139154 WP_149597574.1 NZ_CP043624:3457666-3457917 [Glutamicibacter sp. ZJUTW]
MSISASEARKTLFPLIEQVNDDRQAVEIVSRKGNAVLMAADEYAAWQETAYLFRSPASARRLLDAYERARSGITETHELD
WDE

Download         Length: 252 bp

>AT139154 NZ_CP058527:480179-480379 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References