Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3231213..3231358 Replicon chromosome
Accession NZ_CP043597
Organism Klebsiella pneumoniae strain WCHKP085031

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3231220..3231322 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3231213..3231358 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7D33_RS15870 3226745..3228178 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
B7D33_RS15875 3228294..3228533 + 240 WP_002911393.1 YebV family protein -
B7D33_RS15880 3228631..3228822 + 192 WP_002911395.1 YebW family protein -
B7D33_RS15885 3228819..3229472 - 654 WP_004175436.1 protein-serine/threonine phosphatase -
B7D33_RS15890 3229629..3230597 + 969 WP_074181864.1 VirK/YbjX family protein -
B7D33_RS15895 3230702..3230845 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3231213..3231358 + 146 - - Antitoxin
- 3231220..3231322 - 103 - - Toxin
B7D33_RS15900 3231481..3231819 - 339 WP_002911404.1 YebY family protein -
B7D33_RS15905 3231836..3232705 - 870 WP_094644986.1 copper homeostasis membrane protein CopD -
B7D33_RS15910 3232709..3233083 - 375 WP_004151448.1 CopC domain-containing protein YobA -
B7D33_RS15915 3233196..3233426 + 231 WP_002911406.1 DNA polymerase III subunit theta -
B7D33_RS15920 3233505..3234164 + 660 WP_002911407.1 exodeoxyribonuclease X -
B7D33_RS15925 3234168..3236228 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T139137 NZ_CP043597:c3231322-3231220 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT139137 NZ_CP043597:3231213-3231358 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References