Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1822086..1822231 Replicon chromosome
Accession NZ_CP043588
Organism Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015096

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1822122..1822224 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1822086..1822231 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLR01_RS08855 1817216..1819276 + 2061 WP_004151449.1 oligopeptidase B -
CLR01_RS08860 1819280..1819939 - 660 WP_021440386.1 exodeoxyribonuclease X -
CLR01_RS08865 1820018..1820248 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLR01_RS08870 1820361..1820735 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLR01_RS08875 1820739..1821608 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
CLR01_RS08880 1821625..1821963 + 339 WP_002911404.1 YebY family protein -
- 1822086..1822231 - 146 - - Antitoxin
- 1822122..1822224 + 103 - - Toxin
CLR01_RS08885 1822599..1822742 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLR01_RS08890 1822847..1823815 - 969 WP_004151446.1 VirK/YbjX family protein -
CLR01_RS08895 1823972..1824625 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
CLR01_RS08900 1824622..1824813 - 192 WP_002911395.1 YebW family protein -
CLR01_RS08905 1824911..1825150 - 240 WP_002911393.1 YebV family protein -
CLR01_RS08910 1825266..1826699 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T139096 NZ_CP043588:1822122-1822224 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT139096 NZ_CP043588:c1822231-1822086 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References