Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1863055..1863200 Replicon chromosome
Accession NZ_CP043585
Organism Klebsiella pneumoniae subsp. ozaenae strain SCKP020151

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1863091..1863193 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1863055..1863200 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ49_RS08990 (CLQ49_09085) 1858185..1860245 + 2061 WP_004148850.1 oligopeptidase B -
CLQ49_RS08995 (CLQ49_09090) 1860249..1860908 - 660 WP_002911407.1 exodeoxyribonuclease X -
CLQ49_RS09000 (CLQ49_09095) 1860987..1861217 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ49_RS09005 (CLQ49_09100) 1861330..1861704 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ49_RS09010 (CLQ49_09105) 1861708..1862577 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
CLQ49_RS09015 (CLQ49_09110) 1862594..1862932 + 339 WP_002911404.1 YebY family protein -
- 1863055..1863200 - 146 - - Antitoxin
- 1863091..1863193 + 103 - - Toxin
CLQ49_RS09020 (CLQ49_09120) 1863568..1863711 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLQ49_RS09025 (CLQ49_09125) 1863816..1864784 - 969 WP_014907334.1 VirK/YbjX family protein -
CLQ49_RS09030 (CLQ49_09130) 1864941..1865594 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
CLQ49_RS09035 (CLQ49_09135) 1865591..1865782 - 192 WP_002911395.1 YebW family protein -
CLQ49_RS09040 (CLQ49_09140) 1865880..1866119 - 240 WP_002911393.1 YebV family protein -
CLQ49_RS09045 (CLQ49_09145) 1866235..1867668 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T139078 NZ_CP043585:1863091-1863193 [Klebsiella pneumoniae subsp. ozaenae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT139078 NZ_CP043585:c1863200-1863055 [Klebsiella pneumoniae subsp. ozaenae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References