Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2079734..2079879 Replicon chromosome
Accession NZ_CP043580
Organism Klebsiella pneumoniae strain SCKP020018

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2079770..2079872 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2079734..2079879 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6M74_RS10000 2074864..2076924 + 2061 WP_004151449.1 oligopeptidase B -
C6M74_RS10005 2076928..2077587 - 660 WP_002911407.1 exodeoxyribonuclease X -
C6M74_RS10010 2077666..2077896 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C6M74_RS10015 2078009..2078383 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C6M74_RS10020 2078387..2079256 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
C6M74_RS10025 2079273..2079611 + 339 WP_002911404.1 YebY family protein -
- 2079734..2079879 - 146 - - Antitoxin
- 2079770..2079872 + 103 - - Toxin
C6M74_RS10030 2080247..2080390 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C6M74_RS10035 2080495..2081463 - 969 WP_014907334.1 VirK/YbjX family protein -
C6M74_RS10040 2081620..2082273 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C6M74_RS10045 2082270..2082461 - 192 WP_002911395.1 YebW family protein -
C6M74_RS10050 2082559..2082798 - 240 WP_002911393.1 YebV family protein -
C6M74_RS10055 2082914..2084347 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T139056 NZ_CP043580:2079770-2079872 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT139056 NZ_CP043580:c2079879-2079734 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References