Detailed information of TA system TA139035

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 476177..476520
• Replicon: chromosome
• Accession: NZ_CP043570
• Organism: Stenotrophomonas acidaminiphila strain T25-65

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: F0P98_RS01995
• Protein ID: WP_056932450.1
• Coordinates: 476386..476520 (+)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: F0P98_RS01990
• Protein ID: WP_056932451.1
• Coordinates: 476177..476329 (+)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F0P98_RS01975	472742..473497	-	756	WP_056932454.1	helix-turn-helix domain-containing protein	-
F0P98_RS01980	473517..474914	-	1398	WP_182212677.1	oxygen-independent coproporphyrinogen III oxidase	-
F0P98_RS01985	475129..476049	+	921	WP_056932452.1	arginase	-
F0P98_RS01990	476177..476329	+	153	WP_056932451.1	entericidin A/B family lipoprotein	Antitoxin
F0P98_RS01995	476386..476520	+	135	WP_056932450.1	entericidin A/B family lipoprotein	Toxin
F0P98_RS02000	476713..476934	+	222	WP_054667983.1	CsbD family protein	-
F0P98_RS02005	477013..477795	-	783	WP_056932449.1	hypothetical protein	-
F0P98_RS02010	477905..479197	+	1293	WP_182212678.1	tryptophan--tRNA ligase	-
F0P98_RS02015	479240..479539	+	300	WP_182212679.1	hypothetical protein	-
F0P98_RS02020	479665..480663	+	999	WP_182212680.1	MBL fold metallo-hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4596.46 Da
• Isoelectric Point: 10.2040

>T139035 WP_056932450.1 NZ_CP043570:476386-476520 [Stenotrophomonas acidaminiphila]
MKRTVALMMLSLFSIAVLSGCNTVAGAGKDVQKAGEKVEDAAKR

Nucleotide

• Length: 135 bp

>T139035 NZ_CP058342:c797432-797058 [Escherichia coli]
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTACTGGACCAGCATTACAGCCTTACGCTGAATGACACACCGTTCGTGGATGAACGCGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTGGAAAAATACGCACTGGTACGAACTGACCAGCCGGGATTC
AGCGCAGGAGCCTCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCCGGGCAACAGGCCTGATGACCCGCCA
CAACTACAGAACGGTGAACAATATCACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5201.13 Da
• Isoelectric Point: 7.7213

>AT139035 WP_056932451.1 NZ_CP043570:476177-476329 [Stenotrophomonas acidaminiphila]
MKRVLMLALLAVFSAGMLSACNTVAGAGKDMQKAGEKVEDKAHDCSDGKC

Nucleotide

• Length: 153 bp

>AT139035 NZ_CP058342:c797890-797522 [Escherichia coli]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCGGT
TCAGAGATGCGGATGCGTACCCTCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGAAATTAATGCTCACCAGTGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCTGAAACGAAAAAGTAA