Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2105439..2105710 Replicon chromosome
Accession NZ_CP043542
Organism Escherichia coli strain F2_81

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2105569..2105672 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2105439..2105710 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPH39_RS10105 2101994..2102656 - 663 WP_000944256.1 exodeoxyribonuclease X -
CPH39_RS10110 2102680..2103336 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
CPH39_RS10115 2103438..2103668 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CPH39_RS10120 2103807..2104181 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CPH39_RS10125 2104185..2105057 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
CPH39_RS10130 2105070..2105411 + 342 WP_000976472.1 YebY family protein -
- 2105439..2105710 - 272 - - Antitoxin
- 2105569..2105672 + 104 - - Toxin
CPH39_RS10135 2105807..2106463 + 657 WP_089637581.1 protein-serine/threonine phosphatase -
CPH39_RS10140 2106464..2106655 - 192 WP_001313035.1 YebW family protein -
CPH39_RS10145 2106760..2106996 - 237 WP_096220293.1 YebV family protein -
CPH39_RS10150 2107114..2108553 - 1440 WP_053884247.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T138976 NZ_CP043542:2105569-2105672 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT138976 NZ_CP043542:c2105710-2105439 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References