138966

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4472652..4473037 Replicon chromosome
Accession NZ_CP043540
Organism Xanthomonas translucens pv. undulosa strain LW16

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag F0H32_RS19270 Protein ID WP_003469322.1
Coordinates 4472652..4472786 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag F0H32_RS19275 Protein ID WP_003469323.1
Coordinates 4472885..4473037 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0H32_RS19255 4469094..4470017 - 924 WP_003469319.1 MBL fold metallo-hydrolase -
F0H32_RS19260 4470080..4471480 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
F0H32_RS19265 4471591..4472442 + 852 WP_058359131.1 hypothetical protein -
F0H32_RS19270 4472652..4472786 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
F0H32_RS19275 4472885..4473037 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
F0H32_RS19280 4473182..4474104 - 923 Protein_3781 arginase -
F0H32_RS19290 4474510..4475328 - 819 WP_047325438.1 SPOR domain-containing protein -
F0H32_RS19295 4475338..4476078 - 741 WP_003469293.1 type III pantothenate kinase -
F0H32_RS19300 4476075..4477094 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
F0H32_RS19305 4477199..4477462 + 264 WP_038238001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T138966 WP_003469322.1 NZ_CP043540:c4472786-4472652 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T138966 NZ_CP043540:c4472786-4472652 [Xanthomonas translucens pv. undulosa]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT138966 WP_003469323.1 NZ_CP043540:c4473037-4472885 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT138966 NZ_CP058308:c4648900-4648610 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References