Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1030666..1031171 Replicon chromosome
Accession NZ_CP043540
Organism Xanthomonas translucens pv. undulosa strain LW16

Toxin (Protein)


Gene name relE Uniprot ID A0A2S0NY60
Locus tag F0H32_RS04660 Protein ID WP_003468814.1
Coordinates 1030666..1030923 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag F0H32_RS04665 Protein ID WP_003468816.1
Coordinates 1030920..1031171 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0H32_RS04630 1025898..1027247 + 1350 WP_047324600.1 aminodeoxychorismate synthase component I -
F0H32_RS04635 1027317..1028384 + 1068 WP_170873989.1 endolytic transglycosylase MltG -
F0H32_RS04640 1028381..1029049 + 669 WP_003468811.1 dTMP kinase -
F0H32_RS04645 1029046..1030023 + 978 WP_003468812.1 DNA polymerase III subunit delta' -
F0H32_RS04650 1030020..1030373 + 354 WP_003468813.1 PilZ domain-containing protein -
F0H32_RS04660 1030666..1030923 - 258 WP_003468814.1 Txe/YoeB family addiction module toxin Toxin
F0H32_RS04665 1030920..1031171 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F0H32_RS04670 1031327..1032091 + 765 WP_003468819.1 endonuclease -
F0H32_RS04675 1032088..1032810 - 723 WP_058362494.1 ArsR family transcriptional regulator -
F0H32_RS04680 1032934..1033383 + 450 WP_003468823.1 nuclear transport factor 2 family protein -
F0H32_RS04685 1033636..1034241 + 606 WP_058362496.1 hypothetical protein -
F0H32_RS04690 1034409..1034684 - 276 WP_003468826.1 hypothetical protein -
F0H32_RS04695 1035019..1035309 + 291 WP_003468827.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T138965 WP_003468814.1 NZ_CP043540:c1030923-1030666 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T138965 NZ_CP058308:c4340645-4340472 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT138965 WP_003468816.1 NZ_CP043540:c1031171-1030920 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT138965 NZ_CP058308:c4340969-4340673 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S0NY60

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References