Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-YefM
Location 2367431..2367957 Replicon chromosome
Accession NZ_CP043504
Organism Protaetiibacter larvae strain KACC 19322

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FLP23_RS11205 Protein ID WP_149325933.1
Coordinates 2367691..2367957 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FLP23_RS11200 Protein ID WP_149325932.1
Coordinates 2367431..2367694 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLP23_RS11165 2362947..2363588 - 642 WP_149325927.1 NAD(P)H-binding protein -
FLP23_RS11170 2363629..2363820 - 192 WP_149325928.1 PspC domain-containing protein -
FLP23_RS11175 2363931..2364959 + 1029 WP_149325929.1 NYN domain-containing protein -
FLP23_RS11180 2365018..2365674 + 657 WP_149325930.1 NAD(P)-binding domain-containing protein -
FLP23_RS11185 2365730..2365882 + 153 Protein_2197 acyl-CoA desaturase -
FLP23_RS11190 2365866..2366498 - 633 WP_149325931.1 GyrI-like domain-containing protein -
FLP23_RS11195 2366509..2366976 - 468 WP_149326299.1 hypothetical protein -
FLP23_RS11200 2367431..2367694 + 264 WP_149325932.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FLP23_RS11205 2367691..2367957 + 267 WP_149325933.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FLP23_RS11210 2368028..2368537 + 510 WP_149326300.1 GNAT family N-acetyltransferase -
FLP23_RS11215 2368547..2370064 - 1518 WP_149325934.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
FLP23_RS11220 2370078..2371589 - 1512 WP_149325935.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
FLP23_RS11225 2371586..2371894 - 309 WP_210413862.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(6-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 9950.48 Da        Isoelectric Point: 10.2313

>T138903 WP_149325933.1 NZ_CP043504:2367691-2367957 [Protaetiibacter larvae]
VTVYTVEFTSAAARELRKLDPLIRRRVLDGIAALQGDPRPPNSTKLVGADNAWRIRVGDYRVLYEVADALVLVTVFKVGH
RREVYEAR

Download         Length: 267 bp

>T138903 NZ_CP043504:2367691-2367957 [Protaetiibacter larvae]
GTGACCGTCTACACGGTCGAGTTCACCTCCGCCGCGGCGCGCGAACTGCGGAAACTCGATCCGCTCATCCGGCGGCGGGT
GCTCGACGGCATCGCGGCCCTGCAGGGCGATCCGCGACCGCCGAACTCGACGAAACTCGTCGGCGCCGACAACGCCTGGC
GCATCCGCGTCGGCGACTACCGCGTGCTCTACGAGGTCGCCGACGCACTCGTCCTCGTGACCGTCTTCAAGGTCGGCCAC
CGCCGCGAGGTGTACGAGGCGCGATGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9549.70 Da        Isoelectric Point: 4.4709

>AT138903 WP_149325932.1 NZ_CP043504:2367431-2367694 [Protaetiibacter larvae]
MSTLNRSVTTRALREDLADVVGRVVYARERIGVTRHGKLAAVVIGVEDLELLESLEDARDAAEFRAAREADDGVRVSLDE
LRGELDA

Download         Length: 264 bp

>AT138903 NZ_CP058277:c3091123-3090794 [Mycobacterium marinum]
ATGAGCATGGCACGCAACTGGCGTGATATCCGTGCCGACGCCATCGCGCAGGGGCGCCTGGACCCCGCCCGCGCCGATGC
CGCGCGCAACGAGATGCACGACGCGGTCCAGGCCCACCGGCTCGCCGAAATTCGCAAAGCCCAAGGCCACAGACGTCAGG
CCGACGTCGCTGTCCTGATGGGGGTTTCGCAAGCGCGAGTGTCGAAGTTGGAGAGCGGCGACCTGTCGCACACCCAGCTT
GGCACGCTCCAGTCTTACGTGGCGGCGTTGGGCGGCAGCCTCCGGGTCGTCGCCGAGTTTGACGAGAAGACCGTGGAGCT
GACAACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References