Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1670961..1671760 Replicon chromosome
Accession NZ_CP043504
Organism Protaetiibacter larvae strain KACC 19322

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FLP23_RS07885 Protein ID WP_149325348.1
Coordinates 1670961..1671464 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag FLP23_RS07890 Protein ID WP_149325349.1
Coordinates 1671461..1671760 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLP23_RS07875 1666993..1669623 + 2631 WP_149325346.1 site-specific DNA-methyltransferase -
FLP23_RS07880 1670278..1670964 + 687 WP_149325347.1 hypothetical protein -
FLP23_RS07885 1670961..1671464 - 504 WP_149325348.1 GNAT family N-acetyltransferase Toxin
FLP23_RS07890 1671461..1671760 - 300 WP_149325349.1 DUF1778 domain-containing protein Antitoxin
FLP23_RS07895 1671854..1674640 + 2787 WP_149325350.1 DEAD/DEAH box helicase -
FLP23_RS07900 1675020..1675661 + 642 WP_149325351.1 hypothetical protein -
FLP23_RS07905 1675658..1675867 + 210 WP_149325352.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1669639..1680281 10642


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(8-96)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18167.94 Da        Isoelectric Point: 7.1337

>T138901 WP_149325348.1 NZ_CP043504:c1671464-1670961 [Protaetiibacter larvae]
MSQLTPPRKLEKTDVRVGFESGAAELDEWFAKYAWENQAANNAITYVITDGTRVVAYYSITMAAIEKAAAPPAMLKGSRP
AQIPCILLARLAVDKRFAGQGLGWELLRDALLRSVGLSESIGAAAVLIHCRDESARAFYLANGDFLQSPVDELHLVAPMK
ALRSYVG

Download         Length: 504 bp

>T138901 NZ_CP043504:c1671464-1670961 [Protaetiibacter larvae]
ATGAGCCAACTCACACCACCGCGAAAGCTCGAAAAGACAGACGTCCGAGTCGGATTCGAGAGCGGAGCCGCTGAGCTCGA
TGAGTGGTTCGCGAAATACGCATGGGAGAACCAGGCAGCTAACAACGCGATCACCTATGTCATTACCGATGGCACCCGCG
TGGTTGCTTACTACTCGATCACCATGGCAGCGATCGAGAAGGCTGCGGCCCCGCCTGCAATGCTCAAGGGATCCCGCCCT
GCGCAGATCCCGTGCATCCTTCTCGCAAGGCTCGCAGTCGACAAGAGATTTGCGGGGCAGGGTCTCGGTTGGGAACTGCT
TCGTGACGCACTACTCCGGTCGGTCGGCCTCAGCGAAAGCATCGGGGCTGCGGCTGTTCTCATTCACTGTCGCGATGAGA
GTGCTCGCGCTTTCTATCTAGCCAACGGCGACTTCCTCCAGTCGCCAGTGGATGAACTCCACCTTGTTGCTCCGATGAAG
GCGTTGCGGTCCTATGTTGGCTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11439.80 Da        Isoelectric Point: 7.0188

>AT138901 WP_149325349.1 NZ_CP043504:c1671760-1671461 [Protaetiibacter larvae]
MPDITTEPRSTKNQRINLRATERQEAVLRRAAEATDHSLTDFILSSAVEQAQRVLADRRWFSATEEQYAEFLRLLDEPLP
STAKFDRLFARRSRFAEAG

Download         Length: 300 bp

>AT138901 NZ_CP043504:c1671760-1671461 [Protaetiibacter larvae]
ATGCCTGACATCACGACTGAGCCGCGTTCGACGAAGAACCAGCGCATCAACCTCCGCGCGACCGAGCGACAAGAGGCAGT
GCTCCGCCGTGCTGCAGAAGCTACCGACCACAGTCTCACGGATTTCATTCTGAGTAGCGCGGTCGAGCAAGCGCAGCGGG
TGCTCGCAGATCGTCGTTGGTTCAGTGCGACCGAGGAGCAGTACGCAGAATTCCTTCGTCTGCTGGATGAGCCGCTTCCT
TCGACAGCAAAGTTTGACCGACTGTTCGCTCGTCGTTCGCGCTTCGCCGAAGCTGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References