138896

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4347372..4347757 Replicon chromosome
Accession NZ_CP043500
Organism Xanthomonas translucens pv. undulosa strain P3

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag F0H33_RS18985 Protein ID WP_003469322.1
Coordinates 4347372..4347506 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag F0H33_RS18990 Protein ID WP_003469323.1
Coordinates 4347605..4347757 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0H33_RS18970 4343807..4344730 - 924 WP_003469319.1 MBL fold metallo-hydrolase -
F0H33_RS18975 4344800..4346200 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
F0H33_RS18980 4346311..4347162 + 852 WP_058364719.1 hypothetical protein -
F0H33_RS18985 4347372..4347506 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
F0H33_RS18990 4347605..4347757 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
F0H33_RS18995 4347902..4348824 - 923 Protein_3731 arginase -
F0H33_RS19005 4349230..4350048 - 819 WP_047325438.1 SPOR domain-containing protein -
F0H33_RS19010 4350058..4350798 - 741 WP_047325439.1 type III pantothenate kinase -
F0H33_RS19015 4350795..4351814 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
F0H33_RS19020 4351919..4352182 + 264 WP_038238001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T138896 WP_003469322.1 NZ_CP043500:c4347506-4347372 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T138896 NZ_CP043500:c4347506-4347372 [Xanthomonas translucens pv. undulosa]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT138896 WP_003469323.1 NZ_CP043500:c4347757-4347605 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT138896 NZ_CP058259:c418410-418213 [Actinomyces sp. oral taxon 169]
GTGCGAACCACCGTGACACTCAGTGATGACCTCATTGCCAACGCTCAGGAACTCACGGGCATCACTGAGCGCACCGAGCT
GCTGCGGGCCGGCCTGGAGACCCTGGTCAGAGTGGAGAGCGCACGTCGCCTTGCAGCTCTCGGCGGCTCTGATCGGACGG
CGAGCGCCGCTCCACGACGTCGGACGGCCAGCCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References