Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1012989..1013494 Replicon chromosome
Accession NZ_CP043500
Organism Xanthomonas translucens pv. undulosa strain P3

Toxin (Protein)


Gene name relE Uniprot ID A0A2S0NY60
Locus tag F0H33_RS04535 Protein ID WP_003468814.1
Coordinates 1012989..1013246 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag F0H33_RS04540 Protein ID WP_003468816.1
Coordinates 1013243..1013494 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0H33_RS04505 1008221..1009570 + 1350 WP_058363674.1 aminodeoxychorismate synthase component I -
F0H33_RS04510 1009640..1010707 + 1068 WP_170873989.1 endolytic transglycosylase MltG -
F0H33_RS04515 1010704..1011372 + 669 WP_003468811.1 dTMP kinase -
F0H33_RS04520 1011369..1012346 + 978 WP_058363673.1 DNA polymerase III subunit delta' -
F0H33_RS04525 1012343..1012696 + 354 WP_003468813.1 PilZ domain-containing protein -
F0H33_RS04535 1012989..1013246 - 258 WP_003468814.1 Txe/YoeB family addiction module toxin Toxin
F0H33_RS04540 1013243..1013494 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F0H33_RS04545 1013650..1014414 + 765 Protein_875 endonuclease -
F0H33_RS04550 1014411..1015133 - 723 WP_003468821.1 ArsR family transcriptional regulator -
F0H33_RS04555 1015257..1015706 + 450 WP_003468823.1 nuclear transport factor 2 family protein -
F0H33_RS04560 1015959..1016564 + 606 WP_038237759.1 hypothetical protein -
F0H33_RS04565 1016732..1017007 - 276 WP_149569733.1 hypothetical protein -
F0H33_RS04570 1017342..1017632 + 291 WP_003468827.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T138895 WP_003468814.1 NZ_CP043500:c1013246-1012989 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T138895 NZ_CP043500:c1013246-1012989 [Xanthomonas translucens pv. undulosa]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACTACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAAGCGCAT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAGGGCGTCGGCAAGCCAGAACCGCTACGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACATCGCATCGTGTACAAGGTCGAGGCGGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT138895 WP_003468816.1 NZ_CP043500:c1013494-1013243 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT138895 NZ_CP043500:c1013494-1013243 [Xanthomonas translucens pv. undulosa]
ATGGACACCATCACCTATAGCGCTGCACGCGCCGCCCTTGCGGACACCATGGAGCGCGTCGTCAACAACCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGCTGTCGCTTGAAGACTACAAGGCGATGGAGGAAACCGCCTACC
TGCTCCGCAGTCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCCCAGCTCGAGGCCGGTCGCGGCAAGGCACGGGAC
CTGGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S0NY60

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References