Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 468634..469230 Replicon chromosome
Accession NZ_CP043498
Organism Rhizobium grahamii strain BG7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FZ934_RS02340 Protein ID WP_153269749.1
Coordinates 468634..468879 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FZ934_RS02345 Protein ID WP_153269750.1
Coordinates 468883..469230 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZ934_RS02315 464281..464727 + 447 WP_153269745.1 Rrf2 family transcriptional regulator -
FZ934_RS02320 464823..465041 + 219 WP_153269746.1 ribbon-helix-helix domain-containing protein -
FZ934_RS02325 465035..465406 + 372 WP_153269747.1 type II toxin-antitoxin system VapC family toxin -
FZ934_RS02330 465403..466764 - 1362 WP_153269748.1 chloride channel protein -
FZ934_RS02335 466929..468577 - 1649 Protein_455 choline dehydrogenase -
FZ934_RS02340 468634..468879 + 246 WP_153269749.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
FZ934_RS02345 468883..469230 + 348 WP_153269750.1 helix-turn-helix transcriptional regulator Antitoxin
FZ934_RS02350 469241..470710 - 1470 WP_153269751.1 betaine-aldehyde dehydrogenase -
FZ934_RS02355 470707..471306 - 600 WP_153269752.1 transcriptional regulator BetI -
FZ934_RS02360 471446..471994 + 549 WP_153269753.1 HdeD family acid-resistance protein -
FZ934_RS02365 472181..472411 + 231 WP_153269754.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(58-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8927.44 Da        Isoelectric Point: 11.1284

>T138892 WP_153269749.1 NZ_CP043498:468634-468879 [Rhizobium grahamii]
MRAVSYTKAASKSLSRMQPKRQAAIRAKVDAFARGEAVDLKRLTGSSLVRIRVDDDRVIIDEQTGLVLVIKVGPRGGIYK
E

Download         Length: 246 bp

>T138892 NZ_CP043498:468634-468879 [Rhizobium grahamii]
ATGAGGGCCGTTTCCTACACCAAAGCTGCATCTAAGAGCCTTAGCCGGATGCAGCCGAAGCGTCAGGCGGCAATCAGGGC
CAAGGTCGACGCATTCGCGCGTGGCGAAGCTGTGGATCTCAAACGATTGACCGGTAGCTCGCTTGTTCGAATCCGGGTGG
ACGATGACAGGGTCATAATCGATGAGCAGACCGGACTTGTCCTGGTCATCAAGGTCGGGCCACGCGGCGGGATCTACAAG
GAGTAA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12826.69 Da        Isoelectric Point: 4.2793

>AT138892 WP_153269750.1 NZ_CP043498:468883-469230 [Rhizobium grahamii]
MGSFEKTVIGGKPFVLVPEEEFEDMLDIIDANRIMARVAAGEETFPAELVYELLETDSRIRTYRIYRKMTATELAEAVGI
SQPYLSDIENGKKSGSVDVLKRIAVALRVDLDDIA

Download         Length: 348 bp

>AT138892 NZ_CP058253:2847622-2847767 [Enterobacter roggenkampii]
AACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References