Detailed information of TA system TA138890

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 231755..232313
• Replicon: chromosome
• Accession: NZ_CP043498
• Organism: Rhizobium grahamii strain BG7

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: FZ934_RS01160
• Protein ID: WP_153269565.1
• Coordinates: 232050..232313 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: FZ934_RS01155
• Protein ID: WP_153269564.1
• Coordinates: 231755..232069 (-)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FZ934_RS01120	226811..227557	-	747	WP_153269557.1	L,D-transpeptidase	-
FZ934_RS01125	227769..228398	+	630	WP_153269558.1	DNA-3-methyladenine glycosylase I	-
FZ934_RS01130	228395..228886	+	492	WP_153269559.1	hypothetical protein	-
FZ934_RS01135	228887..229591	-	705	WP_153269560.1	HAD family hydrolase	-
FZ934_RS01140	229831..230853	+	1023	WP_153269561.1	aldo/keto reductase	-
FZ934_RS01145	230897..231256	-	360	WP_153269562.1	DUF305 domain-containing protein	-
FZ934_RS27930	231423..231569	+	147	WP_203437282.1	hypothetical protein	-
FZ934_RS01155	231755..232069	-	315	WP_153269564.1	BrnA antitoxin family protein	Antitoxin
FZ934_RS01160	232050..232313	-	264	WP_153269565.1	BrnT family toxin	Toxin
FZ934_RS01165	232379..233134	-	756	WP_153269566.1	hypothetical protein	-
FZ934_RS01170	233270..234790	+	1521	WP_153269567.1	histidine--tRNA ligase	-
FZ934_RS01180	234970..236088	+	1119	WP_153269568.1	ATP phosphoribosyltransferase regulatory subunit	-
FZ934_RS01185	236088..236783	+	696	WP_153269569.1	ATP phosphoribosyltransferase	-
FZ934_RS01190	236864..237310	-	447	WP_153269570.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-77)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (28-101)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9685.21 Da
• Isoelectric Point: 5.8355

>T138890 WP_153269565.1 NZ_CP043498:c232313-232050 [Rhizobium grahamii]
MKIVWDEPKRLANLDKHGLDFADLDEVFFLGAILQPAKRGRLMAIGRFADGSIAVIFAVLGSQGISIVSMRPARKSERRL
LDDSEED

Nucleotide

• Length: 264 bp

>T138890 NZ_CP058253:c1073100-1072882 [Enterobacter roggenkampii]
ATGTCTGATAAACCACTCACAAAAATCGATTATTTGATGCGCTTACGACGTTGTCAGTCAATTGACACCCTCGAACGCGT
GATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCCGTATTTTATTCAGCCGCTGACCATCGTCTTGCTGAGC
TGACCATGAATAAGTTGTATGACAAAATCCCTACTTCTGTATGGAAATTTGTCCGTTAA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 12021.51 Da
• Isoelectric Point: 8.5442

>AT138890 WP_153269564.1 NZ_CP043498:c232069-231755 [Rhizobium grahamii]
MTAKKTELQIEFKEGRGYSKEDWDDVSDSPEWTEEDFKNARPFAEVFPELAESIRRSRGRPAVEQPKRQISLRLDPDVID
AFKATGKGWQGRINEALRKAAKLR

Nucleotide

• Length: 315 bp

>AT138890 NZ_CP058253:c1073502-1073128 [Enterobacter roggenkampii]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAACCTTGATGAAAGCAACCATGGCTGGGTAAACGACCCAACGTCTGCCATCAATTTACAGTTGAATGAGCTGATAGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGTAGTTACGGCATTAACGCCCAGGATTTGCAAAAATGGCGTAAATCGGGAAACCGGCT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCGGTTAGCCTTTCCTGTTAA