Detailed information of TA system TA138802

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 3385266..3385771
• Replicon: chromosome
• Accession: NZ_CP043476
• Organism: Xanthomonas hyacinthi strain CFBP 1156

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FZ025_RS14985
• Protein ID: WP_046978179.1
• Coordinates: 3385266..3385523 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: FZ025_RS14990
• Protein ID: WP_003468816.1
• Coordinates: 3385520..3385771 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FZ025_RS14955	3381405..3382466	+	1062	WP_046981403.1	endolytic transglycosylase MltG	-
FZ025_RS14960	3382463..3383131	+	669	WP_046981401.1	dTMP kinase	-
FZ025_RS14965	3383128..3384105	+	978	WP_104558745.1	DNA polymerase III subunit delta'	-
FZ025_RS14970	3384102..3384455	+	354	WP_046978181.1	PilZ domain-containing protein	-
FZ025_RS14980	3384692..3385237	+	546	WP_046978180.1	hypothetical protein	-
FZ025_RS14985	3385266..3385523	-	258	WP_046978179.1	Txe/YoeB family addiction module toxin	Toxin
FZ025_RS14990	3385520..3385771	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FZ025_RS14995	3385924..3386686	+	763	Protein_2942	endonuclease	-
FZ025_RS15000	3386683..3387405	-	723	WP_046978178.1	ArsR family transcriptional regulator	-
FZ025_RS15005	3387528..3387977	+	450	WP_046978177.1	nuclear transport factor 2 family protein	-
FZ025_RS15010	3388183..3388689	+	507	WP_208803816.1	hypothetical protein	-
FZ025_RS15015	3389237..3389527	+	291	WP_046978176.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10173.68 Da
• Isoelectric Point: 9.6587

>T138802 WP_046978179.1 NZ_CP043476:c3385523-3385266 [Xanthomonas hyacinthi]
VTLQFSDNAWEDYLYWQQTDKKMLKRVNDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGILLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T138802 NZ_CP043476:c3385523-3385266 [Xanthomonas hyacinthi]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACTACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAAGCGCGT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAAGGCGTCGGCAAGCCAGAACCGCTGCGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACATCGCATCGTCTACAAGGTCGAGGCTGGCATCCTGCTGATCGCGCAGGTG
CGCTACCACTATGTTTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT138802 WP_003468816.1 NZ_CP043476:c3385771-3385520 [Xanthomonas hyacinthi]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT138802 NZ_CP058226:4106601-4106975 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9