138800

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2058675..2059061 Replicon chromosome
Accession NZ_CP043476
Organism Xanthomonas hyacinthi strain CFBP 1156

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag FZ025_RS09290 Protein ID WP_003469322.1
Coordinates 2058927..2059061 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag FZ025_RS09285 Protein ID WP_046978720.1
Coordinates 2058675..2058827 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZ025_RS09255 2053910..2054806 + 897 WP_046978726.1 hypothetical protein -
FZ025_RS09260 2054991..2055731 - 741 WP_046978725.1 twin-arginine translocase subunit TatC -
FZ025_RS09265 2055728..2056234 - 507 WP_046978724.1 Sec-independent protein translocase protein TatB -
FZ025_RS09270 2056252..2056485 - 234 WP_046978723.1 Sec-independent protein translocase subunit TatA -
FZ025_RS09275 2056561..2057445 - 885 WP_046978722.1 SH3 domain-containing-like protein 1 -
FZ025_RS09280 2057608..2058531 + 924 WP_046978721.1 arginase -
FZ025_RS09285 2058675..2058827 + 153 WP_046978720.1 entericidin A/B family lipoprotein Antitoxin
FZ025_RS09290 2058927..2059061 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
FZ025_RS09295 2059125..2059967 - 843 WP_104558352.1 hypothetical protein -
FZ025_RS09300 2060079..2061371 + 1293 WP_046978718.1 tryptophan--tRNA ligase -
FZ025_RS09305 2061652..2062575 + 924 WP_046978717.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T138800 WP_003469322.1 NZ_CP043476:2058927-2059061 [Xanthomonas hyacinthi]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T138800 NZ_CP058226:2031548-2031650 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5337.31 Da        Isoelectric Point: 6.8934

>AT138800 WP_046978720.1 NZ_CP043476:2058675-2058827 [Xanthomonas hyacinthi]
MKRLLTLMLLTLFCAGMLTGCNTMAGAGKDMQEAGQKVEHKADDCSDGKC

Download         Length: 153 bp

>AT138800 NZ_CP058226:c2031657-2031512 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure

References