Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 259844..260409 Replicon chromosome
Accession NZ_CP043476
Organism Xanthomonas hyacinthi strain CFBP 1156

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FZ025_RS01220 Protein ID WP_046981455.1
Coordinates 260089..260409 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FZ025_RS01215 Protein ID WP_046981456.1
Coordinates 259844..260101 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZ025_RS01195 256332..257300 - 969 WP_158185619.1 IS5 family transposase -
FZ025_RS01200 257401..258417 - 1017 WP_158185509.1 IS30 family transposase -
FZ025_RS01205 258393..258833 - 441 WP_158185510.1 biotin/lipoyl-binding protein -
FZ025_RS01210 259452..259637 + 186 Protein_235 transposase -
FZ025_RS01215 259844..260101 + 258 WP_046981456.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FZ025_RS01220 260089..260409 + 321 WP_046981455.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FZ025_RS01225 260419..263421 - 3003 WP_104559034.1 ligand-binding sensor domain-containing diguanylate cyclase -
FZ025_RS01230 263839..264585 - 747 WP_046981453.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
FZ025_RS01235 264771..265241 - 471 WP_046981452.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12158.01 Da        Isoelectric Point: 8.9866

>T138797 WP_046981455.1 NZ_CP043476:260089-260409 [Xanthomonas hyacinthi]
MAEIVWSEPALADLDAIADYIALESPVAASELVKRIFDHVEQLVEHPDSGSRPQELGRSRYRQIVEPPCRVFYRHDGHKV
FILHVMRSERLLRKGRLASRAKQAKV

Download         Length: 321 bp

>T138797 NZ_CP058226:354089-354436 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATGCCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTGTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGTGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9683.24 Da        Isoelectric Point: 9.7761

>AT138797 WP_046981456.1 NZ_CP043476:259844-260101 [Xanthomonas hyacinthi]
MRTELVTTLKRQATELLADIERDKQPILITQHGLPSAYLVDVETYQLMQQRMAVLEGIARGEQAVAEGRVATHAEARKRL
ARWLK

Download         Length: 258 bp

>AT138797 NZ_CP058226:354436-354735 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References