Detailed information of TA system TA138792

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-RelB
• Location: 6358969..6359474
• Replicon: chromosome
• Accession: NZ_CP043449
• Organism: Mucilaginibacter gossypii strain P4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DIU38_RS27290
• Protein ID: WP_090532546.1
• Coordinates: 6359220..6359474 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DIU38_RS27285
• Protein ID: WP_090532548.1
• Coordinates: 6358969..6359223 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DIU38_RS27275	6355029..6355798	+	770	Protein_5461	lytic transglycosylase domain-containing protein	-
DIU38_RS27280	6356014..6358860	+	2847	WP_112655611.1	excinuclease ABC subunit UvrA	-
DIU38_RS27285	6358969..6359223	+	255	WP_090532548.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
DIU38_RS27290	6359220..6359474	+	255	WP_090532546.1	Txe/YoeB family addiction module toxin	Toxin
DIU38_RS27295	6359520..6361307	+	1788	WP_112655609.1	DUF885 domain-containing protein	-
DIU38_RS27300	6361443..6362327	-	885	WP_112655608.1	UbiA family prenyltransferase	-
DIU38_RS27305	6362458..6362985	+	528	WP_112655606.1	YceI family protein	-
DIU38_RS27310	6363004..6364113	+	1110	WP_112655604.1	type III polyketide synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10205.76 Da
• Isoelectric Point: 9.3469

>T138792 WP_090532546.1 NZ_CP043449:6359220-6359474 [Mucilaginibacter gossypii]
VKIIFQNPAWEDYLYWQTTDKSILKKINSLIKEIERTPYEGSGKPEPLKHNLAGWWSRRINLEHRLIYRVEADAIFILQC
RYHY

Nucleotide

• Length: 255 bp

>T138792 NZ_CP058223:4377199-4377585 [Escherichia coli]
ATGGGTGTGTATAAGGCAAGACGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAGGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGTTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAACCAAAGAAATCGAAGATGATGAACTGGCGGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTTTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9776.16 Da
• Isoelectric Point: 5.7377

>AT138792 WP_090532548.1 NZ_CP043449:6358969-6359223 [Mucilaginibacter gossypii]
MEITTYTAFRQQLKSFLDKVRNDHKPLVVTSANAEDIVVISKADYESMEETFYLLKSPKNAERLLHGIQEYEKGLGKERK
LLEE

Nucleotide

• Length: 255 bp

>AT138792 NZ_CP043449:6358969-6359223 [Mucilaginibacter gossypii]
ATGGAGATCACAACTTACACTGCCTTCAGGCAGCAACTAAAATCTTTTTTAGATAAGGTGCGGAATGATCATAAGCCTTT
GGTAGTGACAAGTGCCAATGCCGAAGATATTGTTGTGATATCGAAAGCTGATTACGAAAGCATGGAGGAAACTTTCTATC
TTTTAAAAAGCCCTAAAAATGCAGAAAGATTACTTCATGGTATCCAAGAATATGAAAAAGGTTTAGGCAAGGAAAGAAAG
CTACTTGAAGAGTGA