138790

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1999114..2000153 Replicon plasmid unnamed1
Accession NZ_CP043441
Organism Cupriavidus campinensis strain MJ1

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag FZF10_RS27775 Protein ID WP_149138778.1
Coordinates 1999578..2000153 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag FZF10_RS27770 Protein ID WP_149138777.1
Coordinates 1999114..1999581 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FZF10_RS27750 1994262..1995272 - 1011 WP_149139376.1 acyl-CoA/acyl-ACP dehydrogenase -
FZF10_RS27755 1995444..1996952 - 1509 WP_149138775.1 anion permease -
FZF10_RS27760 1997105..1997767 - 663 WP_149138776.1 DNA oxidative demethylase AlkB -
FZF10_RS27765 1998058..1999020 + 963 WP_149139377.1 glycoside hydrolase family protein -
FZF10_RS27770 1999114..1999581 + 468 WP_149138777.1 helix-turn-helix domain-containing protein Antitoxin
FZF10_RS27775 1999578..2000153 + 576 WP_149138778.1 PIN domain-containing protein Toxin
FZF10_RS27780 2000167..2001251 - 1085 Protein_1803 alpha/beta hydrolase -
FZF10_RS27785 2001531..2002952 - 1422 Protein_1804 flagellar hook-length control protein FliK -
FZF10_RS27790 2002968..2003420 - 453 WP_149138779.1 flagellar export protein FliJ -
FZF10_RS27795 2003413..2004858 - 1446 WP_149139378.1 flagellar protein export ATPase FliI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - plc / adeG / acrB / hcp/tssD / vipB/tssC / katA / hsiC1/vipB / hsiB1/vipA / motA / cheA / cheW / cheB / cheY / flhA / flgC / flgG / flgI / fliI / ddhA 1..2786414 2786414


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-129)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21642.95 Da        Isoelectric Point: 8.2989

>T138790 WP_149138778.1 NZ_CP043441:1999578-2000153 [Cupriavidus campinensis]
MRCSPFTAVYDACVLYPAPLRDFLMELALTGSFRARWSREIHDEWQRNLLRNRPDLSAERLTRTVRLMNEAIPDSVVSGH
LPLIDGLVLPDPGDRHVLAAAIRCNASVIVTFNQKDFPQTALDPFGIEAQHPDEFIDNLFNLDPGVVLTAARRQRARFRQ
PPMKADHYLSVLLRQGLVQTTKNLVGFRAVL

Download         Length: 576 bp

>T138790 NZ_CP043441:1999578-2000153 [Cupriavidus campinensis]
ATGAGGTGTTCCCCGTTCACGGCGGTGTACGACGCATGTGTCCTGTACCCGGCGCCGTTGCGGGACTTCCTGATGGAACT
GGCGCTGACCGGCAGCTTCCGCGCCCGCTGGAGCCGCGAGATTCACGACGAATGGCAGCGCAACCTGCTGCGGAACCGGC
CGGATCTCAGCGCGGAACGCCTGACCCGGACAGTCCGGCTCATGAACGAAGCGATTCCAGACTCGGTAGTGAGCGGGCAC
TTGCCCCTGATCGACGGACTTGTCCTGCCCGACCCGGGCGATCGCCATGTCCTCGCGGCAGCCATTCGTTGCAACGCCAG
CGTGATCGTGACCTTCAATCAGAAGGACTTCCCCCAGACCGCCCTGGACCCGTTCGGCATCGAGGCACAGCACCCCGACG
AATTCATCGACAACCTGTTTAATCTGGACCCCGGCGTCGTGCTGACCGCGGCACGGCGGCAGCGGGCACGATTCCGCCAG
CCGCCGATGAAAGCGGACCACTACCTGAGCGTGCTGCTCCGGCAGGGTCTCGTGCAGACGACCAAGAATCTCGTCGGCTT
TCGCGCCGTCCTCTGA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17104.61 Da        Isoelectric Point: 6.3385

>AT138790 WP_149138777.1 NZ_CP043441:1999114-1999581 [Cupriavidus campinensis]
MTSPTLQKTTLPLEGEVQAAVRGQRALAAFLATRVETQRIQIFDENNEAHQIELPTSALRLLLDILAELANGNAVKIVPV
HAELTTQEAADILNVSRPHLVKLLEDGVLPFHRTGKHRRVRFADLMAYKAVRAETSDAAMDALAREARDLGMGYE

Download         Length: 468 bp

>AT138790 NZ_CP043441:1999114-1999581 [Cupriavidus campinensis]
ATGACCTCTCCCACCCTTCAGAAGACGACCCTGCCGTTGGAAGGCGAGGTCCAGGCCGCCGTGCGCGGCCAGCGCGCACT
TGCAGCATTTCTCGCCACGCGTGTGGAAACGCAACGCATCCAGATCTTCGACGAGAACAATGAGGCGCATCAAATCGAGC
TGCCTACCTCGGCGCTACGCTTGCTGCTCGACATCCTCGCCGAACTGGCCAACGGCAACGCCGTCAAGATCGTGCCGGTT
CACGCCGAACTGACCACGCAGGAAGCTGCGGACATCCTCAACGTGTCTCGACCCCATCTCGTGAAATTGCTCGAAGACGG
CGTGCTGCCGTTCCACCGCACCGGCAAGCACCGGCGCGTGCGCTTCGCAGACCTGATGGCCTACAAGGCCGTCCGCGCCG
AGACCAGCGACGCCGCCATGGACGCACTGGCCCGCGAAGCGCGCGACCTGGGCATGGGCTACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References